[HTML][HTML] β-amyloid pathology and hippocampal atrophy are independently associated with memory function in cognitively healthy elderly

AL Svenningsson, E Stomrud, PS Insel, N Mattsson… - Scientific reports, 2019 - nature.com
… , we found that (1) Aβ positivity, HV, and cortical thickness (temporal and frontal) were
associated with worse memory, with independent effects of Aβ and HV on memory; (2) the Aβ …

[HTML][HTML] Amyloid load, hippocampal volume loss, and diffusion tensor imaging changes in early phases of brain aging

S Haller, ML Montandon, C Rodriguez… - Frontiers in …, 2019 - frontiersin.org
… 70 years of age with an increase of amyloid burden in the presence … cortex, mesial temporal
lobe, parietal lobe, as well as … Another recent contribution indicated that PIB PET β-amyloid’…

In vivo measures of tau burden are associated with atrophy in early Braak stage medial temporal lobe regions in amyloid-negative individuals

SR Das, L Xie, LEM Wisse, N Vergnet, R Ittyerah… - Alzheimer's & …, 2019 - Elsevier
… higher Braak stage was associated with greater anterior hippocampal atrophy [26]… temporal
lobe in primary age-related tauopathy, including relating tau burden with longitudinal atrophy

Beta amyloid deposition maps onto hippocampal and subiculum atrophy in dementia with Lewy bodies

E Mak, PC Donaghy, E McKiernan, MJ Firbank… - … of aging, 2019 - Elsevier
… quantification of Aβ burden and how it relates to clinical and … have demonstrated that
hippocampal atrophy in AD is … thinning was constrained to the temporal cortex in our sample of …

Longitudinal trajectory of Amyloid‐related hippocampal subfield atrophy in nondemented elderly

L Zhang, E Mak, A Reilhac, HY Shim… - Human brain …, 2020 - Wiley Online Library
Hippocampal atrophy and abnormal β-Amyloid (Aβ) … showed longitudinal atrophy irrespective
of Aβ burden in NCI and … pinpoint the exact neocortex Aβ-hippocampal atrophy pathway(s), …

Brain β-amyloid and atrophy in individuals at increased risk of cognitive decline

IK Martikainen, N Kemppainen… - American Journal …, 2019 - Am Soc Neuroradiology
… load and temporal lobe atrophy in clinically healthy elderly is … with PIB+ findings with temporal
lobe atrophy in this study are … burden in the temporal neocortex is related to hippocampal

Neuropathological and sociodemographic factors associated with the cortical amyloid load in aging and Alzheimer's disease

SP da Silva, CCM de Castro, LN Rabelo… - Geroscience, 2024 - Springer
… in the influence of age, sex, and education on the Aβ burden. … associated with Aβ accumulation
in the cerebral cortex of CU … Aβ plaque density in the cortex and hippocampus [68]. We …

[HTML][HTML] Association of cortical microstructure with amyloid-β and tau: impact on cognitive decline, neurodegeneration, and clinical progression in older adults

E Rodriguez-Vieitez, V Montal, J Sepulcre, C Lois… - Molecular …, 2021 - nature.com
… Higher cMD at baseline predicted faster hippocampal atrophy and clinical progression to …
into the neocortex. Our finding that increased cMD is associated with tau but not Aβ burden is …

Hippocampal subregional volume changes in elders classified using positron emission tomography‐based Alzheimer's biomarkers of βamyloid deposition and …

G Busatto Filho, FLS Duran, P Squarzoni… - Journal of …, 2021 - Wiley Online Library
hippocampus in cognitively impaired or unimpaired elderly … subjects due to errors during
hippocampal segmentation (… Aβ deposition-hippocampal atrophy correlations discussed above. …

Hippocampal volume loss, brain amyloid accumulation, and APOE status in cognitively intact elderly subjects

S Haller, ML Montandon, C Rodriguez… - Neurodegenerative …, 2020 - karger.com
temporal cortex volume in MCI, with only a modest effect on … of well-educated elderly with
no significant vascular burden; this … ciated with hippocampal atrophy rate in normal aging and …