Pamrevlumab, an anti-connective tissue growth factor therapy, for idiopathic pulmonary fibrosis (PRAISE): a phase 2, randomised, double-blind, placebo-controlled …

L Richeldi, ERF Pérez, U Costabel, C Albera… - … Lancet Respiratory …, 2020 - thelancet.com
… Our findings include positive results on multiple efficacy outcomes, including lung
function and, for the first time, quality of life and chest imaging with a quantitative high-resolution …

Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified …

JY Chang, RJ Mehran, L Feng, V Verma, Z Liao… - The Lancet …, 2021 - thelancet.com
… was assessed according to the Common Terminology Criteria for Adverse Events (version
4.0). One PET-… Pulmonary function tests were recommended at 12 months but not required. All …

The therapy of idiopathic pulmonary fibrosis: what is next?

V Somogyi, N Chaudhuri, SE Torrisi… - … Respiratory Review, 2019 - Eur Respiratory Soc
… and nintedanib led to a significant reduction in lung function decline, there is still no cure for
… -β-overexpressing animal model of fibrosis [93]. A phase I trial (NCT01254409) assessing

[HTML][HTML] Senolytics in idiopathic pulmonary fibrosis: results from a first-in-human, open-label, pilot study

JN Justice, AM Nambiar, T Tchkonia, NK LeBrasseur… - …, 2019 - thelancet.com
… No changes in laboratory tests suggestive of hepatic or renal toxicity were found, and
pulmonary function was unchanged. While effects of DQ on circulating SASP factors were …

[HTML][HTML] Animal models for COVID-19

C Muñoz-Fontela, WE Dowling, SGP Funnell, PS Gsell… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of
coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the …

Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the H eart F ailure A ssociation (HFA), the E …

J Čelutkienė, R Pudil… - European journal of …, 2020 - Wiley Online Library
… Given the common use of 18 F-FDG PET to monitor cancer progression, this phenomenon of
… Cardiac FDG-PET can be used to assess for ICI-mediated myocarditis in cases where CMR …

Silica‐associated lung disease: an old‐world exposure in modern industries

H Barnes, NSL Goh, TL Leong, R Hoy - Respirology, 2019 - Wiley Online Library
… impact of silica dust on respiratory function was observed by … This perpetual cycle leads to
further alveolitis and fibrosis.22 … Early animal studies have contributed to our understanding …

[HTML][HTML] Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

PUC Dinh, D Paudel, H Brochu, KD Popowski… - Nature …, 2020 - nature.com
… to measure pulmonary function and evaluate the respiratory … since their discovery within
exosomes 22 . It is believed that … This could be due to the difference in the animal models. …

Value of pre-therapy 18F-FDG PET/CT radiomics in predicting EGFR mutation status in patients with non-small cell lung cancer

J Zhang, X Zhao, Y Zhao, J Zhang, Z Zhang… - European journal of …, 2020 - Springer
… In this paper, 18 F-FDG PET/CT radiomics, which extracts the texture features of PET and
CT … a PET/CT radiomics-based model to predict EGFR mutation status in patients with lung

Pulmonary effects of inhaled cannabis smoke

DP Tashkin, MD Roth - The American journal of drug and alcohol …, 2019 - Taylor & Francis
… on lung function, airway inflammation and smoking-related lung disease. Objectives: Review
the potential effects of cannabis smoking on respiratory symptoms, lung function… and animal