25-Hydroxycholesterol as a signaling molecule of the nervous system
UG Odnoshivkina, EA Kuznetsova, AM Petrov - Biochemistry (Moscow), 2022 - Springer
Cholesterol is an essential component of plasma membrane and precursor of biological
active compounds, including hydroxycholesterols (HCs). HCs regulate cellular homeostasis of …
active compounds, including hydroxycholesterols (HCs). HCs regulate cellular homeostasis of …
Effects of oxysterols on immune cells and related diseases
… by B cells in response to TLR activation is responsible for a mechanism that negatively
regulates the local and systemic adaptive immune response by the innate immune system [68]. …
regulates the local and systemic adaptive immune response by the innate immune system [68]. …
[图书][B] 25-Hydroxycholesterol Regulates Inflammation by Activating Integrin-FAK Signaling Pathway
SM Pokharel - 2020 - rex.libraries.wsu.edu
… is part of host innate immune response constituting the first … The cells of innate immune
system like macrophages play a … that shapes the innate immune inflammatory response. Our …
system like macrophages play a … that shapes the innate immune inflammatory response. Our …
Cholesterol metabolism: from lipidomics to immunology
WJ Griffiths, Y Wang - Journal of lipid research, 2022 - ASBMB
… immune system. Here, we review recent findings related to the roles of oxysterols in immunology.
… regulation of the adaptive immune system by the innate immune system in response to …
… regulation of the adaptive immune system by the innate immune system in response to …
25-hydroxycholesterol inhibits kaposi's sarcoma herpesvirus and epstein-barr virus infections and activates inflammatory cytokine responses
… during latent and lytic infection that block the innate immune response. Previously, we found
that … We observed innate immunity genes that are upregulated by 25HC in the context of …
that … We observed innate immunity genes that are upregulated by 25HC in the context of …
The role of cholesterol 25-hydroxylase in viral infections: Mechanisms and implications
P Yousefi, A Gholami, M Mehrjo, MH Razizadeh… - … -Research and Practice, 2023 - Elsevier
… f) Regulation of inflammation, innate immunity, and adaptive immunity. Overall, the collective
actions of CH25H and 25HC encompass a wide range of antiviral mechanisms, offering a …
actions of CH25H and 25HC encompass a wide range of antiviral mechanisms, offering a …
25‐Hydroxycholesterol metabolism is altered by lung inflammation, and its local administration modulates lung inflammation in mice
P Bottemanne, A Paquot, H Ameraoui… - The FASEB …, 2021 - Wiley Online Library
Inflammation is a critical component of many lung diseases including asthma and acute
lung injury (ALI). Using high‐performance liquid chromatography–mass spectrometry, we …
lung injury (ALI). Using high‐performance liquid chromatography–mass spectrometry, we …
[PDF][PDF] Effects of Oxysterols on Immune Cells and Related Diseases. Cells 2022, 11, 1251
FA de Freitas, D Levy, CO Reichert, E Cunha-Neto… - 2022 - academia.edu
… in inflammation, innate immunity, and subsequent adaptive immune responses through …
that 25-hydroxycholesterol has a potential function in innate immune regulation [68]. In addition, …
that 25-hydroxycholesterol has a potential function in innate immune regulation [68]. In addition, …
[HTML][HTML] Diverse immunoregulatory roles of oxysterols—the oxidized cholesterol metabolites
C Choi, DK Finlay - Metabolites, 2020 - mdpi.com
… This is of particular interest in the context of immunology and … immune responses. Equally,
aberrant metabolic processes including altered cholesterol homeostasis contribute to immune …
aberrant metabolic processes including altered cholesterol homeostasis contribute to immune …
Integrin activation by the lipid molecule 25-hydroxycholesterol induces a proinflammatory response
… inflammation during innate immunity, the subject of this study 12 . The innate immune system
is … PRRs are expressed by cells of the innate immune system, including macrophages and …
is … PRRs are expressed by cells of the innate immune system, including macrophages and …