3′-Daidzein Sulfonate Sodium Protects Against Chronic Cerebral Hypoperfusion-Mediated Cognitive Impairment and Hippocampal Damage via Activity-Regulated …

Q Zeng, Z Huang, J Zhang, R Liu, X Li, J Zeng… - Frontiers in …, 2019 - frontiersin.org
… (DSS) increased Arc expression in the hippocampi of the 2VO … Even so, our study is the first
report to provide evidence of … Arc overexpression promotes DSS-mediated neuroprotection in …

3′-Daidzein Sulfonate Sodium Protects against Glutamate-induced Neuronal Injuries by Regulating NMDA Receptors

R Feng, L Luo, Z Han, Y Qi, H Xiao… - Current …, 2024 - benthamdirect.com
… Our findings provide experimental evidence for the potential … to illustrate the potential
neuroprotective mechanisms of DSS. … vides neuroprotection by promoting the expression of the α7 …

[HTML][HTML] Daidzein alleviates neuronal damage and oxidative stress via GSK3β/Nrf2 pathway in mice

X Wang, Z Yin, X Meng, D Yang, H Meng, C Liao… - Journal of Functional …, 2022 - Elsevier
Daidzein promoted the antioxidant capacity in mice brain … the expression of MAO-B and
SCNA, and promote the … These data suggest that DAI has neuroprotective effect on LPS-…

Neuroprotective Effect of Daidzein Extracted From Pueraria lobate Radix in a Stroke Model Via the Akt/mTOR/BDNF Channel

M Zheng, M Zhou, M Chen, Y Lu, D Shi… - Frontiers in …, 2022 - frontiersin.org
… buffer (0.1% sodium dodecyl sulfate (SDS), 0.5% sodium deoxycholate, 1… to produce
neuroprotective effects and promote the … -3, while daidzein significantly decreased the expression

Daidzein's potential in halting neurodegeneration: unveiling mechanistic insights

L Singh - Naunyn-Schmiedeberg's Archives of Pharmacology, 2024 - Springer
… Furthermore, 3′-daidzein sulfonate sodium (DSS), a water-… delineate that daidzein
also confers neuroprotection by … Daidzein may inhibit oxidative stress by promoting the …

Daidzein Ameliorates Cerebral Ischemic-reperfusion Induced Neuroinflammation in Wistar Rats via Inhibiting NF-κB Signaling Pathway

J Zhang, R Kowsalya - Pharmacognosy Magazine, 2023 - journals.sagepub.com
… analysis confirms daidzein is a potent neuroprotective drug … mixture consisting of 500 µL
sodium phosphate, 200 µL 4mM … Peroxynitrite disrupts the cell membrane and promotes lipid …

Pharmacokinetics, pharmacodynamics, toxicity, and formulations of daidzein: An important isoflavone

AP Laddha, YA Kulkarni - Phytotherapy Research, 2023 - Wiley Online Library
… Self-assembled daidzein with lecithin and sodium bile into … It was also reported that daidzein
showed a neuroprotective … reduced by daidzein treatment and it also promoted caspase-…

Soy isoflavone daidzein protects Neuro2a cells from NO stress via activation of AMPK-PGC1α pathway followed by mitochondrial enhancement

S Ito, H Sasaki, T Gotow, I Suetake, K Nagai - PharmaNutrition, 2023 - Elsevier
… [7], [8] and are known to promote mitochondrial biogenesis [9], [10]. In … for neuroprotection
via mitochondrial enhancement. … with daidzein in the presence of dorsomorphin for 2 h, sodium

Protective effects of 6, 7, 4′-trihydroxyisoflavone, a major metabolite of daidzein, on 6-hydroxydopamine-induced neuronal cell death in SH-SY5Y human …

YH Ko, SH Kwon, SK Kim, BR Lee, KH Hur… - Archives of pharmacal …, 2019 - Springer
… In addition, daidzein has shown neuroprotective effects in 6-… using 8–10% sodium dodecyl
sulfate polyacrylamide gel … , and cleaved caspase-3, thereby promoting neuronal cell survival …

[HTML][HTML] Genistein-3′-sodium sulfonate promotes brain functional rehabilitation in ischemic stroke rats by regulating astrocytes polarization through NF-κB signaling …

R Liu, Y Yu, Q Ge, R Feng, G Zhong, L Luo… - Chemico-Biological …, 2024 - Elsevier
… the neuroprotective effect of genistein-3′-sodium sulfonate (… demonstrated that long-term
administration of GSS treatment … It has been demonstrated that the neuroprotective effects of …