… of prenatal stress in regulating the neural modulation network underlying the prepulse inhibition of the acoustic startle reflex in male Alzheimer's disease mice

Z Jafari, BE Kolb, MH Mohajerani - Cerebral Cortex, 2020 - academic.oup.com
… Third, alteration in the activity of the maternal and fetal … fluorescent that has high specificity
in staining plaques in post… in the PS mice than the controls, the behavioral results and

[HTML][HTML] Life Experience Matters: Enrichment and Stress Can Influence the Likelihood of Developing Alzheimer's Disease via Gut Microbiome

SE Torraville, CM Flynn, TL Kendall, Q Yuan - Biomedicines, 2023 - mdpi.com
stress and the pathogenesis of AD and can increase both and NFTs in animal models of
the disease. Both stress and enrichment have been shown to alter … in their 3xTG-AD mouse

[HTML][HTML] Chronic-antibiotics induced gut microbiota dysbiosis rescues memory impairment and reduces β-amyloid aggregation in a preclinical Alzheimer's disease …

PC Bello-Medina, K Corona-Cervantes… - International Journal of …, 2022 - mdpi.com
… A model for studying AD is the triple transgenic mouse (3xTg-AD), … Here we reported an
increase in total and Aβ1-42 … a social behavior alteration and an increase in oxidative stress

Dissecting the relationship between neuropsychiatric and neurodegenerative disorders

R Gupta, D Advani, D Yadav, RK Ambasta… - Molecular …, 2023 - Springer
… includes progressive neuronal cell death and behavioral changes. NDDs include Alzheimer’…
and schizophrenia, characterized by behavioral changes. Mounting evidence demonstrated …

Therapeutic targeting of casein kinase 1δ/ε in an Alzheimer's disease mouse model

P Adler, J Mayne, K Walker, Z Ning… - Journal of proteome …, 2019 - ACS Publications
… their efficacy in reducing levels and enhancing memory in … it was not altered by PF-670462,
with 3xTg-AD mice in both … can re-establish normal behavioral circadian rhythms when …

[HTML][HTML] FAK-mediated signaling controls amyloid beta overload, learning and memory deficits in a mouse model of Alzheimer's disease

B Saleh, KD Srikanth, T Sneh, L Yue, S Pelech… - International Journal of …, 2022 - mdpi.com
… changes that occur in our 3xTg-AD mice, we performed an … /or to the increase in plaque
production in these mice as … accompanied by overload, altered neuronal morphology, and …

[HTML][HTML] Repetitive Low-Level Blast Exposure Improves Behavioral Deficits and Chronically Lowers Aβ42 in an Alzheimer Disease Transgenic Mouse Model

GP Garcia, R De Gasperi, AE Tschiffely… - Journal of …, 2021 - ncbi.nlm.nih.gov
… enzymes may cause increased production and explain the … show that repetitive exposures
actually improved behavioral … not alter amyloid plaque load, 42 levels and oligomers …

Involvement of brain-derived neurotrophic factor signaling in the pathogenesis of stress-related brain diseases

T Numakawa, R Kajihara - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
… between the alteration of TrkB signaling and chronic stress. … Increased glucocorticoids due
to sustained activation of the HPAaxis contribute to and/or tau pathology, oxidative stress, …

[HTML][HTML] … -phenotype, HPA axis, splenic oxidative stress and frailty in late-stages of dementia, with special concerns on the effects of social isolation: a translational …

A Muntsant, L Giménez-Llort - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
behavioral alterations in 18-month-old female 3xTg-AD mice … an altered response in the
3xTg-AD mice characterized by a … short isolation could increase the activity in 3xTg-AD mice and …

Noise exposure accelerates the risk of cognitive impairment and Alzheimer's disease: Adulthood, gestational, and prenatal mechanistic evidence from animal studies

Z Jafari, BE Kolb, MH Mohajerani - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
… and increases stress hormones that affect brain and behaviour. … High levels of corticosterone
days after NS, and changes in … the stress literature, chronic exposure to high levels of stress