… of prenatal stress in regulating the neural modulation network underlying the prepulse inhibition of the acoustic startle reflex in male Alzheimer's disease mice
… Third, alteration in the activity of the maternal and fetal … fluorescent that has high specificity
in staining Aβ plaques in post… in the PS mice than the controls, the behavioral results and Aβ …
in staining Aβ plaques in post… in the PS mice than the controls, the behavioral results and Aβ …
[HTML][HTML] Life Experience Matters: Enrichment and Stress Can Influence the Likelihood of Developing Alzheimer's Disease via Gut Microbiome
SE Torraville, CM Flynn, TL Kendall, Q Yuan - Biomedicines, 2023 - mdpi.com
… stress and the pathogenesis of AD and can increase both Aβ and NFTs in animal models of
the disease. Both stress and enrichment have been shown to alter … in their 3xTG-AD mouse …
the disease. Both stress and enrichment have been shown to alter … in their 3xTG-AD mouse …
[HTML][HTML] Chronic-antibiotics induced gut microbiota dysbiosis rescues memory impairment and reduces β-amyloid aggregation in a preclinical Alzheimer's disease …
PC Bello-Medina, K Corona-Cervantes… - International Journal of …, 2022 - mdpi.com
… A model for studying AD is the triple transgenic mouse (3xTg-AD), … Here we reported an
increase in total Aβ and Aβ1-42 … a social behavior alteration and an increase in oxidative stress …
increase in total Aβ and Aβ1-42 … a social behavior alteration and an increase in oxidative stress …
Dissecting the relationship between neuropsychiatric and neurodegenerative disorders
… includes progressive neuronal cell death and behavioral changes. NDDs include Alzheimer’…
and schizophrenia, characterized by behavioral changes. Mounting evidence demonstrated …
and schizophrenia, characterized by behavioral changes. Mounting evidence demonstrated …
Therapeutic targeting of casein kinase 1δ/ε in an Alzheimer's disease mouse model
… their efficacy in reducing Aβ levels and enhancing memory in … it was not altered by PF-670462,
with 3xTg-AD mice in both … can re-establish normal behavioral circadian rhythms when …
with 3xTg-AD mice in both … can re-establish normal behavioral circadian rhythms when …
[HTML][HTML] FAK-mediated signaling controls amyloid beta overload, learning and memory deficits in a mouse model of Alzheimer's disease
B Saleh, KD Srikanth, T Sneh, L Yue, S Pelech… - International Journal of …, 2022 - mdpi.com
… changes that occur in our 3xTg-AD mice, we performed an … /or to the increase in Aβ plaque
production in these mice as … accompanied by Aβ overload, altered neuronal morphology, and …
production in these mice as … accompanied by Aβ overload, altered neuronal morphology, and …
[HTML][HTML] Repetitive Low-Level Blast Exposure Improves Behavioral Deficits and Chronically Lowers Aβ42 in an Alzheimer Disease Transgenic Mouse Model
GP Garcia, R De Gasperi, AE Tschiffely… - Journal of …, 2021 - ncbi.nlm.nih.gov
… enzymes may cause increased Aβ production and explain the … show that repetitive exposures
actually improved behavioral … not alter amyloid plaque load, Aβ 42 levels and Aβ oligomers …
actually improved behavioral … not alter amyloid plaque load, Aβ 42 levels and Aβ oligomers …
Involvement of brain-derived neurotrophic factor signaling in the pathogenesis of stress-related brain diseases
T Numakawa, R Kajihara - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
… between the alteration of TrkB signaling and chronic stress. … Increased glucocorticoids due
to sustained activation of the HPAaxis contribute to Aβ and/or tau pathology, oxidative stress, …
to sustained activation of the HPAaxis contribute to Aβ and/or tau pathology, oxidative stress, …
[HTML][HTML] … -phenotype, HPA axis, splenic oxidative stress and frailty in late-stages of dementia, with special concerns on the effects of social isolation: a translational …
A Muntsant, L Giménez-Llort - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
… behavioral alterations in 18-month-old female 3xTg-AD mice … an altered response in the
3xTg-AD mice characterized by a … short isolation could increase the activity in 3xTg-AD mice and …
3xTg-AD mice characterized by a … short isolation could increase the activity in 3xTg-AD mice and …
Noise exposure accelerates the risk of cognitive impairment and Alzheimer's disease: Adulthood, gestational, and prenatal mechanistic evidence from animal studies
… and increases stress hormones that affect brain and behaviour. … High levels of corticosterone
days after NS, and changes in … the stress literature, chronic exposure to high levels of stress …
days after NS, and changes in … the stress literature, chronic exposure to high levels of stress …