The aim of this clinical study was to describe the case of a patient who experienced chronic diarrhea related to seasonal changes that improved with herbal medicine treatment. A patient with diarrhea and globus hystericus was treated following treatment with Hoehyangbanchong-san-hap-Ukgan-san and Gamisachil-tang. A defecation and urination diary, the Bristol Stool Form Scale, and the Visual Analog Scale (VAS) were used to evaluate the effectiveness of this treatment. During treatment, the patient's Bristol Stool Form Scale score changed from Type 7 to Type 4, and the VAS score was significantly decreased. The symptoms of diarrhea and globus hystericus almost subsided. In this case, Korean traditional herbal medicine reduced the clinical symptoms of diarrhea and globus hystericus.