Drug-Induced Fatty Liver Disease (DIFLD): A Comprehensive Analysis of Clinical, Biochemical, and Histopathological Data for Mechanisms Identification and …

E López-Pascual, I Rienda, J Perez-Rojas… - International Journal of …, 2024 - mdpi.com
… In certain individuals, drug-induced steatosis is often accompanied by concomitant injury …
occasionally reported for drugs such as amiodarone, perhexiline, and didanosine [13,37]. …

Inhibition of mitochondrial fatty acid oxidation in drug-induced hepatic steatosis

B Fromenty - Liver Research, 2019 - Elsevier
perhexiline and pirprofen were withdrawn after marketing. (ii) Drugs such as amiodarone and
perhexiline … (iii) For some drugs including APAP, 40 , 41 L-asparaginase, 42 erythromycin, …

Towards personalized management of drug interactions: from drug-drug-interaction to drug-drug-gene-interaction

A Bahar - 2020 - research.rug.nl
… using lansoprazole and warfarin concomitantly had a greater … CYP2D6 inhibitors (terbinafine,
perhexiline, and quinidine) … Additionally, amiodarone and celecoxib in their interactions …

[HTML][HTML] Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): an expert opinion meeting report

RJ Andrade, GP Aithal, YS De Boer, R Liberal… - Journal of …, 2023 - Elsevier
… as malignancy or DILI due to another concomitant drug. ChILI shows less … case of possible
AIH related to SARS-CoV-2 vaccination was published. Several case reports and case series

Phenoconversion of cytochrome P450 metabolism: a systematic review

SD Klomp, ML Manson, HJ Guchelaar… - Journal of Clinical …, 2020 - mdpi.com
… started therapy with the weak CYP2D6 inhibitor amiodarone [… , the drug interaction with
amiodarone would have had a … the effect of (1) concomitant drugs and other extrinsic factors …

Iatrogenic immune-mediated neuropathies: diagnostic, epidemiological and mechanistic uncertainties for causality and implications for clinical practice

HS Goedee, S Attarian, T Kuntzer… - Journal of Neurology …, 2021 - jnnp.bmj.com
report suggested possible relation of GBS after surgery, but establishing possible causal
relation in this case series … antecedent infections, and concomitant use of drugs (eg, tacrolimus …

How to integrate CYP2D6 phenoconversion into clinical pharmacogenetics: a tutorial

EJ Cicali, AL Elchynski, KJ Cook… - Clinical …, 2021 - Wiley Online Library
… The CYP2D6 drug metabolizing enzyme is susceptible to inhibition by concomitant drugs,
which can lead to a clinical phenotype that is different from the genotype-based phenotype, a …

Drug-Induced Liver Injury

A Maheshwari, S Ranka - Shackelford's Surgery of the Alimentary Tract, 2 …, 2019 - Elsevier
… Patients need to be educated regarding the possible drug interactions of concomitant
drugs and alcohol. Finally, patients who suffer an episode of DILI should be warned to avoid …

[PDF][PDF] Clinical Background and Evaluation of Drug-Induced Prolongation of QT Interval

MD Takao Katoh - academia.edu
… Class III antiarrhythmic drugs including sotalol, nifekalant, dofetilide and amiodarone exhibit
… serum concentration due to drug interaction when another drug is prescribed concomitantly. …

Role of the surgical pathologist in diagnosis of drug-induced liver injury: recognizing specific patterns of drug injury

S Chopra, S Gawrieh, R Vuppalanchi… - Advances in Anatomic …, 2021 - journals.lww.com
… , 65 there was a case report each of bland … perhexiline maleate and 4,4′
diethylaminoethoxyhexestrol, 149,151 both of which are cationic amphiphilic drugs similar to …