… To determine if BATF is intrinsically required for CD8 + T cell-mediated tumor control, we
utilized a … In this study, we established the critical role of the IL-21–BATF pathway in maintaining …

… a previously unappreciated role for the transcription factor BATF in maintaining a permissive
… important roles in chronic viral control. Notably, although no significant difference in BATF …

… -21 was critical to sustain CD8 + T cell responses and viral control. … effective in enhancing
CD8 + T cell-mediated immunity. … Despite the critical role T helper cells play in sustaining both …

… In this study, we established the critical role of the IL-21–BATF pathway in maintaining …
A critical role of IL-21-induced BATF in sustaining CD8-T-cell-mediated chronic viral control. …

… There is a specific protein called BATF that plays an important role in reducing T-cell … to
control chronic viral infections [Citation37], indicating the crucial role of IL-21 in maintaining CD8 …

… To determine if BATF is intrinsically required for CD8+ T cell-mediated tumor control, we …
, we established the critical role of the IL-21–BATF pathway in maintaining functional tumor-…

… CD8 T cell-mediated immunopathology in the brain [56]. … IL21R signaling also induces
BATF in CD8 T cells that may … ) pathway which plays an important role in T cell metabolism and …

… effector function of CD8 + T cells expressing IL-21-induced IL-… CD8 + T cell-mediated immune
responses against viruses … study, we provide novel insight into the critical role of IL-21 for …

… important role in viral infections, especially chronic viral … IL-21-induced basic leucine
zipper transcription factor ATF-… and is important for maintaining the effector function of CD8 + …

… Batf and Irf4, but not Batf alone, were sufficient to increase … major role for Batf and Irf4 in
shaping the transcriptome and epigenome of CD8 + T cells, due to their effects on a subset of key …