… ) cells for type 1 and type 17 signature (top right), tissue repair (… of the complex functions
of immunity to the microbiota, our … that accelerated repair is not associated with altered pain …

… we can consider pain perception as a complex network between immune cells and the
nervous system (Ren and Dubner 2010). Indeed, it has been found that receptors of immune cells …

… gut microbiota–immune system axis can reduce the pain experience and contribute to the
resolution of neuropathic pain. This Review provides an overview of the immune mechanisms …

… immune cells, to modulate induction and maintenance of central sensitisation. Thus, we
propose that gut microbiota regulates pain in … system, and targeting gut microbiota by diet and …

… a possible role in microbiota in pain mechanisms, our purpose … hypothesis of microbiota
targeting in neuropathic pain states. … interaction of gut microbiota with the host immune system, …

… , neuron–immune signalling pathways can be exploited to facilitate pathogen survival. Here,
we discuss the role of nociceptor interactions with the immune system in pain and infection …

… impact on microbiota’s composition and its influence on pain … gut microbiota and both visceral
and inflammatory pain and … to pain can induce some autonomic, endocrine and immune …

… are identified to elicit alteration of pain sensitivity via inducing immune activation [10]. …
Thus, we conclude that gut microbiota plays a dual role by acting on the TLR-mediated pain-…

… IL-17 along with immunoregulatory and tissue repair factors, … Following injury, IL-17 plays
dual roles in protecting the host, … in mouse models of epilepsy, MS, and pain (112–114). In a …

… microbiota in visceral, inflammatory, and neuropathic pain states, including fibromyalgia,
migraine, cancer and chemotherapy-associated pain. … gut microbiome-host immune system [37]. …