… from RNA sequencing (RNA-seq) data. The mutational landscape of 3,217 primary breast
cancer … Large-scale projects such as TCGA and SCAN-B generate vast amounts of data, but …

… samples, enabling studies of somatic mutagenesis in large-scale cohorts, across genetic …
inferred from the sequencing data (using Piccard’s software). This analysis revealed that, for …

… Large-scale studies analyzing DNA sequencing data are needed to better distinguish … the
disease while considering the nonpathogenic landscape of mutations. Such findings may have …

… large-scale prospective clinical sequencing program using the Fudan-BC panel, and
comprehensively analyze the clinical and genomic … A pairwise analysis revealed that the PI3K and …

… enrichment of mutations in coding and putative regulatory regions. Our analysis reveals that
the first cell division after fertilization produces ~3.4 mutations, followed by 2–3 mutations in …

… Using whole-transcriptome sequencing, we analyzed RNA from granulocytes of 104 … for
which mutations in the splicing machinery have been described. This analysis revealed that the 3…

… -neoplastic tissues were subjected to high-throughput transcriptome sequencing. … mutations
in neoplastic cells, but large-scale mutation profiling is not available for each tumour. RNA-…

… This study comprehensively reported the real-world genomic characteristics of large-scale
patients with pancreatic cancer by clinical sequencing from China which is conducive to …

… The high-precision single-cell RNA sequencing protocol we used was a modified STRT-…
before treatment, cells basically do not experience large-scale cell death, so the possibility of …

… workflows to process large-scale data within clinically … cWGTS analyses revealed a profoundly
rearranged genome … patterns demonstrating that cancer genomic landscape can be fully …