Evaluation of testicular toxicity upon fetal exposure to bisphenol A using an organ culture method
… Here, we evaluated BPA toxicity on fetal testes using an in vitro organ culture system. Mouse
fetal testes sampled at 15.5 days post coitus were cultured in a medium containing BPA for …
fetal testes sampled at 15.5 days post coitus were cultured in a medium containing BPA for …
Evaluation of resmethrin toxicity to neonatal testes in organ culture
HJ Park, WY Lee, M Zhang, KH Hong… - Toxicological …, 2020 - academic.oup.com
Resmethrin is a widely used pyrethroid insecticide, which causes low toxicity in mammals.
However, its toxicity in testes has not been fully investigated. Therefore, we evaluated the …
However, its toxicity in testes has not been fully investigated. Therefore, we evaluated the …
[HTML][HTML] Human amnion mesenchymal stem cells restore spermatogenesis in mice with busulfan-induced testis toxicity by inhibiting apoptosis and oxidative stress
C Qian, Q Meng, J Lu, L Zhang, H Li… - Stem cell research & …, 2020 - Springer
… for TUNEL assay and SCP3 immunofluorescence. A TUNEL … meiosis in a busulfan-induced
testis toxicity mouse model … -induced testis toxicity mouse model to evaluate testicular cell …
testis toxicity mouse model … -induced testis toxicity mouse model to evaluate testicular cell …
Mouse embryo assay for human in vitro fertilization quality control: a fresh look
N Esfandiari, A Gubista - Journal of Assisted Reproduction and Genetics, 2020 - Springer
… chemically defined BGJB medium in the presence of mouse fallopian tube cells [4]. In the …
or porcine embryos will detect embryo toxicity the same way that the mouse embryos do in a …
or porcine embryos will detect embryo toxicity the same way that the mouse embryos do in a …
Reproductive and embryological toxicity of lead acetate in male mice and their offspring and mitigation effects of quercetin
… and vas deferens were used for RNA extraction. Total RNA, isolated from the samples of
two mice in … (A) Sperm binding assay in mice, sperm and oocyte pronuclei stained blue; (B) …
two mice in … (A) Sperm binding assay in mice, sperm and oocyte pronuclei stained blue; (B) …
A male germ cell assay and supporting somatic cells: its application for the detection of phase specificity of genotoxins in vitro
K Habas, MH Brinkworth… - Journal of Toxicology and …, 2020 - Taylor & Francis
… Data obtained using the STAPUT methodology revealed that the … to testicular and reproductive
toxicity in vivo. In addition, these data indicate that STAPUT isolation of rodent testicular …
toxicity in vivo. In addition, these data indicate that STAPUT isolation of rodent testicular …
Chronic exposure of BPA impairs male germ cell proliferation and induces lower sperm quality in male mice
XX Liu, ZX Wang, F Liu - Chemosphere, 2021 - Elsevier
… barrier, and steroidogenesis production were examined in BPA-treated and control mice
testes. CCK8 assay was used to detect the effect of BPA on the proliferation of GC-1 and GC-2 …
testes. CCK8 assay was used to detect the effect of BPA on the proliferation of GC-1 and GC-2 …
[HTML][HTML] Using alternative test methods to predict endocrine disruption and reproductive adverse outcomes: do we have enough knowledge?
T Svingen, CL Schwartz, AK Rosenmai, L Ramhøj… - Environmental …, 2022 - Elsevier
… and reliable testing strategies using non-animal test methods for predictive toxicology; both
to … production in the testes Neonatally Testosterone production in fetal testes can be markedly …
to … production in the testes Neonatally Testosterone production in fetal testes can be markedly …
Systematic evaluation of graphene quantum dot toxicity to male mouse sexual behaviors, reproductive and offspring health
D Zhang, Z Zhang, Y Wu, K Fu, Y Chen, W Li, M Chu - Biomaterials, 2019 - Elsevier
… in testes) of the testes and epididymides, as well as normal testosterone levels. Female …
, were determined according to the manufacturer's protocols of the appropriate assay kits. …
, were determined according to the manufacturer's protocols of the appropriate assay kits. …
[HTML][HTML] Anogenital distance as a toxicological or clinical marker for fetal androgen action and risk for reproductive disorders
CL Schwartz, S Christiansen, AM Vinggaard… - … of Toxicology, 2019 - Springer
… in rodent toxicity studies aimed at testing compounds for … in mice at early developmental
stages, but suppress at late gestation, whereas no effects are observed in human fetal testis …
stages, but suppress at late gestation, whereas no effects are observed in human fetal testis …