Cytokines use different intracellular mechanisms to upregulate the membrane expression of CX3CR1 in human monocytes

CA Panek, AC Bruballa, GE Pineda, C De Brasi… - Molecular …, 2019 - Elsevier
… (Mo) because CX 3 CR1-CX 3 CL1 interactions might … signals and pathways that underlay
the level of CX 3 CR1 … common pathway underlying the prevention of CX 3 CR1 loss, …

Human CD16+ monocytes promote a pro-atherosclerotic endothelial cell phenotype via CX3CR1–CX3CL1 interaction

E Roy-Chowdhury, N Brauns, A Helmke… - Cardiovascular …, 2021 - academic.oup.com
underlying mechanism is not understood. This study investigated how human CD16 + monocytes
… Whether secondary endothelial signalling is involved in this has not been determined. …

Regulation and function of CX3CR1 and its ligand CX3CL1 in kidney disease

S von Vietinghoff, C Kurts - Cell and Tissue Research, 2021 - Springer
… Systemically, circulating CX3CR1 + monocytes reversibly … Roles of CX 3 CR1 and CX 3
CL1 in kidney diseases. Functional … The underlying mechanisms of differential monocyte

[HTML][HTML] Dorsal root ganglia CX3CR1 expressing monocytes/macrophages contribute to arthritis pain

S Oggero, C Cecconello, R Silva, L Zeboudj… - Brain, Behavior, and …, 2022 - Elsevier
… We focussed on CX 3 CR 1 -monocyte/macrophage … of the mechanisms underlying RA pain
and identify novel analgesic … on whether the FKN/CX 3 CR 1 pair/signalling is involved in the …

CX3CR1–fractalkine axis drives kinetic changes of monocytes in fibrotic interstitial lung diseases

FR Greiffo, V Viteri-Alvarez… - European …, 2020 - Eur Respiratory Soc
… of the underlying cause of ILD, changes in monocyte or … To this end, our cohort is composed
of severe and end-stage … during homing, local signalling interactions, including sources and …

CX3CR1-CCR2-dependent monocyte-microglial signaling modulates neurovascular leakage and acute injury in a mouse model of childhood stroke

J Faustino, S Chip, N Derugin… - Journal of Cerebral …, 2019 - journals.sagepub.com
… In mice with dysfunctional CX3CR1-CCR2 signaling, extravascular albumin leakage is … In
CAIS model, we demonstrate that monocyte/microglial CX3CR1-CCR2 signaling contributes to …

Blockade of the fractalkine–CX3CR1 axis ameliorates experimental colitis by dislodging venous crawling monocytes

Y Kuboi, M Nishimura, W Ikeda… - International …, 2019 - academic.oup.com
is thought to facilitate the rapid recruitment of monocytes to … phenotype of monocytes is
impaired in CX3CR1-deficient mice, … signaling in initiating and sustaining the pathogenic process …

[HTML][HTML] Regulation and biological functions of the CX3CL1-CX3CR1 axis and its relevance in solid cancer: A mini-review

S Rivas-Fuentes, A Salgado-Aguayo… - Journal of …, 2021 - ncbi.nlm.nih.gov
… as monocytes, CD8 + T cells, and NK cells 3 ; and also, by tissue resident cells such as
macrophages and DCs 34 . CX3CR1 expression is … induction of CX3CR1, CX3CL1 signaling was …

Role of the CX3CL1-CX3CR1 axis in renal disease

D Hamdan, LA Robinson - … of Physiology-Renal Physiology, 2021 - journals.physiology.org
… , studying its expression and signaling patterns will aid in … is mediated through interactions
between dendritic cell CX 3 CR1 … transfer of CX 3 CR1 +/+ monocytes into CX 3 CR1 −/− mice, …

Crosstalk between the CX3CL1/CX3CR1 axis and inflammatory signaling pathways in tissue injury

Q Zhuang, J Ou, S Zhang, Y Ming - Current Protein and Peptide …, 2019 - ingentaconnect.com
… recruit monocytes through their specific receptors CX3CR1 and CCR2, which might provide
novel … We have found that CX3CL1/CX3CR1 axis is associated with the above inflammatory …