[HTML][HTML] Activation of adenosine A2A but not A2B receptors is involved in uridine adenosine tetraphosphate-induced porcine coronary smooth muscle relaxation
C Sun, T Jiao, D Merkus, DJ Duncker… - Journal of …, 2019 - Elsevier
… In the present study, Up 4 A-induced porcine coronary SMC relaxation was partially attenuated
by the H … small arteries isolated from slaughterhouse swine (~100 kg, unknown gender) is …
by the H … small arteries isolated from slaughterhouse swine (~100 kg, unknown gender) is …
Adenosine and adenosine receptor-mediated action in coronary microcirculation
Y Zhang, B Wernly, X Cao, SJ Mustafa, Y Tang… - Basic Research in …, 2021 - Springer
… of hypoxia or ischemia in various tissues, adenosine together with ATP and ADP is … induced
relaxation in isolated porcine coronary arterioles or the A 2A R-induced increase in coronary …
relaxation in isolated porcine coronary arterioles or the A 2A R-induced increase in coronary …
Coronary Microvascular Dysfunction in Cardiovascular Disease: Lessons from Large Animal Models
O Sorop, J van de Wouw, D Merkus… - … : From Bench to Bedside, 2020 - Springer
… the different vasoregulatory pathways as … and ADP [41] while in swine, 1h ischemia followed
by 1h reperfusion resulted in impaired relaxation to serotonin, and bradykinin in coronary …
by 1h reperfusion resulted in impaired relaxation to serotonin, and bradykinin in coronary …
Characterisation of P2Y receptor subtypes mediating vasodilation and vasoconstriction of rat pulmonary artery using selective antagonists
MO Dales, C Mitchell, AM Gurney, RM Drummond… - Purinergic …, 2022 - Springer
… blocking P2Y 1 and P2Y 12 receptors in pigs in vivo [15]. Thus… This shows that neither ATP
nor ADP induce vasodilatation … effect in this study on the relaxation of the rIPA evoked by ATP. …
nor ADP induce vasodilatation … effect in this study on the relaxation of the rIPA evoked by ATP. …
[HTML][HTML] Mechanobiology of microvascular function and structure in health and disease: focus on the coronary circulation
MM Brandt, C Cheng, D Merkus, DJ Duncker… - Frontiers in …, 2021 - frontiersin.org
… , as in swine a residual exercise-induced vasodilation upon … In VSMCs, PGI 2 induces
relaxation via protein kinase A (PKA… transcription of many genes involved in vasoregulation (…
relaxation via protein kinase A (PKA… transcription of many genes involved in vasoregulation (…
NO-induced vasodilation correlates directly with BP in smooth muscle-Na/Ca exchanger-1-engineered mice: elevated BP does not attenuate endothelial function
Y Wang, J Zhang, WG Wier, L Chen… - American Journal of …, 2021 - journals.physiology.org
… Previously we showed that isolated KO and control arteries … and relaxation of constricted
arteries by forskolin-induced … on membrane potential of pig coronary artery endothelial cells. …
arteries by forskolin-induced … on membrane potential of pig coronary artery endothelial cells. …
Kynurenine relaxes arteries of normotensive women and those with preeclampsia
SA Worton, HAT Pritchard, SL Greenwood… - Circulation …, 2021 - Am Heart Assoc
… kynurenine-induced relaxation in porcine coronary arteries, 1 and … vasoregulatory axis as
the mechanism by which kynurenine … , arteries isolated from women with preeclampsia relaxed …
the mechanism by which kynurenine … , arteries isolated from women with preeclampsia relaxed …
Vascular endothelial cell biology: an update
A Krüger-Genge, A Blocki, RP Franke… - International journal of …, 2019 - mdpi.com
… It actively controls the degree of vascular relaxation and … into and out of tissues and with
local vasoregulation [59]. This is … , was isolated from the cell culture supernatant of porcine EC […
local vasoregulation [59]. This is … , was isolated from the cell culture supernatant of porcine EC […
Potassium channels in the uterine vasculature: Role in healthy and complicated pregnancies
W Bresnitz, RA Lorca - International Journal of Molecular Sciences, 2022 - mdpi.com
… cardiac output to the uteroplacental circulation, which equates to approximately 1 L/min or
20% of cardiac … Additionally, in non-pregnant guinea pigs, ACh-dependent UtA relaxation was …
20% of cardiac … Additionally, in non-pregnant guinea pigs, ACh-dependent UtA relaxation was …
[HTML][HTML] The calcium signaling mechanisms in arterial smooth muscle and endothelial cells
M Ottolini, SK Sonkusare - Comprehensive Physiology, 2021 - ncbi.nlm.nih.gov
The contractile state of resistance arteries and arterioles is a crucial determinant of blood
pressure and blood flow. Physiological regulation of arterial contractility requires constant …
pressure and blood flow. Physiological regulation of arterial contractility requires constant …