Electrochemical biosensors for whole blood analysis: recent progress, challenges, and future perspectives

S Li, H Zhang, M Zhu, Z Kuang, X Li, F Xu… - Chemical …, 2023 - ACS Publications
… and opportunities to integrate electrochemical sensing platforms. … Lai group has constructed
a prototype peptide-based sensor for human immune deficiency virus (HIV) detection using …

[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids, and …

Circulating tumor cells as biomarkers for renal cell carcinoma: ready for prime time?

A Couto-Cunha, C Jerónimo, R Henrique - Cancers, 2022 - mdpi.com
… Interestingly, epigenetic factors, such as DNA methylation, have also been investigated as
… about RCC biology, enabling the identification of novel molecular targets for therapy and …

immunoassays in DNA damage and instability detection

K Boguszewska, M Szewczuk, S Urbaniak… - Cellular and molecular …, 2019 - Springer
… the DNA damage and instability detection such as sensitivity, selectivity, adaptability, and
possibility of testing samples … In this review, we focus and describe in greater detail the group of …

Emerging biosensing and transducing techniques for potential applications in point-of-care diagnostics

J Qin, W Wang, L Gao, SQ Yao - Chemical Science, 2022 - pubs.rsc.org
… With the advancement of genetics and electrochemical science, we are quite optimistic that
more novel electrochemistry-based methods for detecting nucleic acids will be reported in …

[图书][B] Targeting the epigenome and immune system for diagnosis and treatment of malignancies

A Mehdi - 2022 - search.proquest.com
… ❖ Provided for the first-time a potential role of DNA methylation changes in peripheral T …
most studied epigenetic mechanisms that result in cancer are alterations in DNA methylation, …

[图书][B] … of urinary bladder cancer. On standardized care pathway, computed tomography, artificial intelligence, and a newly developed urine-based cancer marker

S Abuhasanein - 2024 - gupea.ub.gu.se
… In his book "Observationum", we find the earliest known illustration … marker is Bladder
EpiCheck (BE), which is a urine test that employs 15 unique DNA methylation biomarkers to detect

Epigenetic Alterations as an Adaptive Response to Chemotherapy

Rubiada, K Fatima, I Mushtaq, J Kour, A Wani… - Drug Resistance in …, 2024 - Springer
novel strategies for therapeutic intervention. Emphasizing the pivotal roles of DNA methylation
and … DNA methylation is adding a methyl group to cytosine residues, mostly found in CpG …

DNA damage response in cancer therapy and resistance: challenges and opportunities

D Jurkovicova, CM Neophytou, AČ Gašparović… - International Journal of …, 2022 - mdpi.com
DNA repair from NHEJ to HR via 53BP1 binding regulation at the DSB site [45,47]. DNA
methylation is a … investigated as potential novel therapeutic targets. The most promising include …

[HTML][HTML] A pipeline for the development and analysis of extracellular vesicle-based transcriptomic biomarkers in molecular diagnostics

C Grätz, M Schuster, F Brandes, AS Meidert… - Molecular Aspects of …, 2024 - Elsevier
… In this review, we intend to illustrate a RNA biomarker identification pipeline: From patient
identification to blood sampling, EV isolation and characterization, over RNA isolation and …