NSAIDs: Old acquaintance in the pipeline for cancer treatment and prevention─ Structural modulation, mechanisms of action, and bright future

S Ramos-Inza, AC Ruberte, C Sanmartin… - Journal of Medicinal …, 2021 - ACS Publications
… I, nonrandomized No increase in toxicity; optimal biological dose of celecoxib established …
an erlotinib and celecoxib combination in patients with advanced non-small-cell lung cancer

[PDF][PDF] Metronomic chemotherapy and drug repurposing: A paradigm shift in oncology

N Jan, S Sofi, H Qayoom, A Shabir, BU Haq, MA Macha… - Heliyon, 2024 - cell.com
… of the most phase II research for non-small cell lung cancer (NSCLC)… and security of erlotinib
combined with metronomic CBP in … Fluvastatin and celecoxib were used in a phase I trial to …

[HTML][HTML] Optimization of the solvent and in vivo administration route of auranofin in a syngeneic non-small cell lung cancer and glioblastoma mouse model

L Freire Boullosa, J Van Loenhout, C Hermans… - Pharmaceutics, 2022 - mdpi.com
… inhibitor in SB28 GBM tumors at high doses. Taken together, our results and results in
the … gavage and osmotic minipumps) to identify the most optimal method to reduce AF-mediated …

Erlotinib

AA Abdelgalil, HM Al-Kahtani, FI Al-Jenoobi - Profiles of Drug Substances …, 2020 - Elsevier
… for determination of erlotinib in different biological matrices. … ) columns with a mobile phase
combination of 10 mM ammonium … Erlotinib is approved for the treatment of Non-Small Cell

Recent clinical evidence on metronomic dosing in controlled clinical trials: a systematic literature review

V Wichmann, N Eigeliene, J Saarenheimo… - Acta …, 2020 - Taylor & Francis
… to select the optimal dosing of metronomic vinorelbine for advanced non-small-cell lung cancer
patients. Most … A phase II study to evaluate lenalidomide in combination with metronomic-…

[HTML][HTML] In vitro and in silico evaluation of anticancer activity of new indole-based 1, 3, 4-oxadiazoles as EGFR and COX-2 inhibitors

B Sever, MD Altıntop, A Özdemir, G Akalın Çiftçi… - Molecules, 2020 - mdpi.com
… oncogenic driver in non-small cell lung cancer (NSCLC), … has triggered interest in evaluating
the combination of COX-2 and … of the re-docked erlotinib, celecoxib, and compound 2e were …

[PDF][PDF] Abstract CT087: Concentration-dependent early anti-vascular and anti-tumor effects of itraconazole in non-small cell lung cancer (NSCLC)

DE Gerber, FJ Fattah, RA Brekken, R Skelton… - Cancer …, 2019 - drive.google.com
… cyclooxygenase inhibitors, such as celecoxib, for treatment of … We employed the nonlinear
mixed effects model to determineErlotinib plus bevacizumab versus erlotinib alone in patients …

Progress in targeted therapeutic drugs for oral squamous cell carcinoma

L Liu, J Chen, X Cai, Z Yao, J Huang - Surgical oncology, 2019 - Elsevier
… 40% of patients with non-small cell lung cancer(NSCLC) and show … the biological activity
mediated by VEGF, reduces tumor … Moreover, the combination of erlotinib and celecoxib also …

[HTML][HTML] Breaking the crosstalk of the Cellular Tumorigenic Network by low-dose combination therapy in lung cancer patient-derived xenografts

D Gürgen, T Conrad, M Becker, S Sebens… - … Biology, 2022 - nature.com
… To obtain the best experience, we recommend you use a more up to … Most cases of non-small
cell lung cancer (NSCLC) are … etoricoxib was replaced with celecoxib, another drug of the …

[PDF][PDF] Inhalable Formulations to Treat Non-Small Cell Lung Cancer (NSCLC): Recent Therapies and Developments. Pharmaceutics 2023, 15, 139

C Gupta, A Jaipuria, N Gupta - 2022 - academia.edu
… These nanocarriers are of the same size as that of biological … compared to the combination
of naringin and celecoxib in plain … created erlotinib loaded SLNs outperformed free erlotinib in …