Translocator protein distribution volume predicts reduction of symptoms during open-label trial of celecoxib in major depressive disorder

S Attwells, E Setiawan, PM Rusjan, C Xu, C Hutton… - Biological …, 2020 - Elsevier
study reported a negative result within a sample combining 5 … optimal window of PFC TSPO
V T and ACC TSPO V T , and a univariate analysis of variance was performed to determine a …

Comparison of the efficacy and safety of CELBESTA® versus CELEBREX® in patients with rheumatoid arthritis: a 6-week, multicenter, double-blind, double-dummy …

HS Kim, WH Choi, BY Kim, SS Kim… - Journal of …, 2020 - journals.sagepub.com
… In this study, CELBESTA® and CELEBREX® treatment resulted in rapid reduction of pain
in RA patients as assessed by the 100-mm VAS score and DAS28-ESR score. In RA patients, …

Optimal biological dose: a systematic review in cancer phase I clinical trials

J Fraisse, D Dinart, D Tosi, C Bellera, C Mollevi - BMC cancer, 2021 - Springer
… Few articles combining immunotherapy with biological agents and clearly mentioning the
OBD have been identified (n = 3). For those particular cases, OBD was assessed using …

Insight into the colonic disposition of celecoxib in humans

G Lemmens, J Brouwers, J Snoeys, P Augustijns… - European Journal of …, 2020 - Elsevier
assess the optimal time and colonic region to sample tissue for the evaluation of the disposition
of celecoxib, we determined… reflects the low solubility of the compound in combination

Integration analysis of metabolites and single nucleotide polymorphisms improves the prediction of drug response of celecoxib

X Xing, P Ma, Q Huang, X Qi, B Zou, J Wei, L Tao, L Li… - Metabolomics, 2020 - Springer
… In this study, we attempted to combine metabolic biomarkers … to optimal the prediction of
celecoxib pharmacokinetics. Our … better reflects biological phenotype, we only combined genetic …

… as an adjunct to treatment-as-usual in children and youth with obsessive–compulsive disorder: protocol for a single-site randomised quadruple-blind phase II study

C Westwell-Roper, JR Best, D Elbe, M MacFadden… - BMJ open, 2022 - bmjopen.bmj.com
study involving biosample collection for correlative biology; … per day (2–5 mg/kg per dose);
those >25 kg will receive 100 … paediatric dosing in children (maximum 4 mg/kg per dose). The …

[HTML][HTML] Comparison of the benefits of celecoxib combined with anticancer therapy in advanced non-small cell lung cancer: A meta-analysis

W Zhang, L Yi, J Shen, H Zhang, P Luo… - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
… A phase I trial to determine the optimal biological dose of celecoxib when combined with
erlotinib in advanced non-small cell lung cancer. Clinical cancer research: an official journal of …

Effects of Resveratrol Co-Administration on Celecoxib Disposition and Pharmacokinetics in Healthy Volunteers

NI Helal, NM El-Khodary, GA Omran… - Drug …, 2023 - thieme-connect.com
… There was no significant change in the time it takes for celecoxib to reach the maximum
dose of celecoxib and consequently lessen its side effects. RSV and celecoxib combination

Celecoxib and Afatinib synergistic enhance radiotherapy sensitivity on human non-small cell lung cancer A549 cells

P Zhang, E Song, M Jiang, Y Song - … Journal of Radiation Biology, 2021 - Taylor & Francis
… Our current study is designed to address the possibility that the combination of Celecoxib
Citation2014), however, to the best of our knowledge, this is the first report testing the effect of …

Celecoxib as a valuable adjuvant in cutaneous melanoma treated with trametinib

DV Tudor, I Bâldea, DE Olteanu… - International Journal of …, 2021 - mdpi.com
… the dabrafenib and trametinib combination, extending the tumor … However, the optimal dose
should be selected carefully as … melanoma biology and celecoxib’s capabilities are needed. …