… This study investigates the therapeutic efficacy of combining Metformin (MET) and Celecoxib
(… We conducted an optimization process to ascertain the duration required for the complete …

… Progress in molecular biology revealed the … at combining two active compounds in formulating
CXB-loaded CS/FCD NPs, tumor cell lines can be used to determine the best combination …

… a new drug or drug combination to humans, a phase I oncology trial traditionally focuses on
… The BOD was determined at the lowest dose level (of celecoxib) showing optimal biological …

… The ideal chemoprevention agent should demonstrate a biologically plausible mechanism
of … When the combination between celecoxib and DFMO was tested in a randomised clinical …

… In a previous phase 2 study, patients with head and neck cancer … We aimed to do a phase
3 study to substantiate these … combination of weekly methotrexate plus daily celecoxib should …

… excipient combination for a given drug has been determined, … different chemical as well as
biological origins can be utilized … The best-performing excipient composition and mixing ratio …

… The Wnt signaling is an evolutionarily conserved biological … Phase Ib trial is currently
underway involving a combination … , a Phase II clinical trial in CRC patients treated with celecoxib …

… We performed a first-in-human, phase 1 dose-escalation clinical trial of intraperitoneal
cisplatin plus local rintatolimod/IFNα/celecoxib, the CKM combination synergistically promoting …

… and celecoxib (200 mg twice daily). In phase I, they first determined the optimal biological
dose … immune checkpoint inhibitor and metronomic chemotherapy combination in lung cancer (…

… The surfactant/cosurfactant mixture (S mix ) (9 : 1) was mixed with oil … (800 rpm; 2 hour) to
determine the optimal concentration. … changes in w/o to o/w were observed under the biological …