[HTML][HTML] Randomized phase II trial of lymphodepletion plus adoptive cell transfer of tumor-infiltrating lymphocytes, with or without dendritic cell vaccination, in patients …

C Saberian, RN Amaria, AM Najjar… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
… DC in a phase II clinical trial of patients with advanced stage IV … Adoptive cell therapy (ACT)
using autologous tumor-infiltrating … -1 reactive T cells and MART-1 pulsed DC vaccine versus …

[HTML][HTML] … dendritic cells pulsed with allogeneic tumour cell lysate induce tumour-reactive T-cell responses in patients with pancreatic cancer: A phase I study

SP Lau, L Klaase, M Vink, J Dumas, K Bezemer… - … Journal of Cancer, 2022 - Elsevier
tumour lysate-dendritic cell vaccination is feasible and safe in patients with pancreatic
cancer… We previously demonstrated the potency of allogeneic lysate-dendritic cell (DC) …

49P A phase II randomized trial with adjuvant autologous tumor lysate-pulsed dendritic cells (DC) in resected stage III-IV melanoma patients: Preliminary …

L Ridolfi, J Bulgarelli, C Piccinini, S Carloni… - Annals of …, 2021 - annalsofoncology.org
… a phase II randomized study with adjuvant autologous tumor lysate-pulsed DC in resected
stage … Background: Adoptive cell therapy (ACT) is used successfully as a highly personalized …

… dendritic cells pulsed with lysate from an allogeneic hepatic cancer cell line as a treatment for patients with advanced hepatocellular carcinoma: a pilot study

MTA Ghafar, MA Morad, EA El-Zamarany… - International …, 2020 - Elsevier
phase II clinical trial is designed to evaluate the safety and efficacy of immunization with specific
activated anti-HCC dendritic cells in … observed that the tumor lysate pulsed-DCs showed …

[HTML][HTML] A characterization of dendritic cells and their role in immunotherapy in glioblastoma: from preclinical studies to clinical trials

S Srivastava, C Jackson, T Kim, J Choi, M Lim - Cancers, 2019 - mdpi.com
… DCs pulsed with autologous glioma tumor lysate in a Phase I/II trial … Phase I studies and
promising preliminary results, groups aimed to expand clinical trials in DCV into phase II studies

A phase I trial of surgical resection with Gliadel Wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant glioma

JD Rudnick, JM Sarmiento, B Uy, M Nuno… - Journal of Clinical …, 2020 - Elsevier
… A prior phase II trial for GBM showed an expansion of CD8 + T-cells and cytotoxic T-…
our other tumor-lysed dendritic cell studies that reach response rates of up to 44%, this study’s …

Trial watch: Dendritic cell (DC)-based immunotherapy for cancer

RS Laureano, J Sprooten, I Vanmeerbeerk… - …, 2022 - Taylor & Francis
… the pulsing of DCs with TAAs (as peptides or tumor lysate) … , with two studies being worthy
of note: a phase II trial which … , ICT-107 (autologous DCs pulsed with six synthetic peptide …

Trial watch: dendritic cell vaccination for cancer immunotherapy

J Sprooten, J Ceusters, A Coosemans… - …, 2019 - Taylor & Francis
… with TAAs or tumor lysates and stimulated with standard … example, DCs pulsed with TAAs
from GBM stem cells provided … GBM enrolled in a Phase II clinical trial. Citation341 Similarly, …

Complete and long-lasting clinical responses in immune checkpoint inhibitor-resistant, metastasized melanoma treated with adoptive T cell transfer combined with DC …

T Lövgren, M Wolodarski, S Wickström… - …, 2020 - Taylor & Francis
Adoptive cell therapy (ACT) with the transfer of ex vivo-expanded … Dendritic cells can be
generated in vitro from monocytes and pulsed with proteins, peptides or whole-tumor lysates or …

… autologous tumor lysate-loaded dendritic cell vaccination improves survival in patients with newly diagnosed and recurrent glioblastoma: survival results from a phase …

LM Liau, K Ashkan, S Brem, J Campian… - Neuro …, 2022 - academic.oup.com
… (pts) were enrolled in this Phase 2 study, age ≥ 18, KPS ≥ 70… employed the use of total
tumor RNA (TTRNA)-pulsed DCs … for T cell activation in PBMC after adoptive cell therapy. We …