Dendritic cells in cancer immunology and immunotherapy
L Hato, A Vizcay, I Eguren, JL Pérez-Gracia… - Cancers, 2024 - mdpi.com
… of DCs pulsed with tumor lysates in preclinical breast cancer (BC… Further clinical trials with
DCV pulsed with HER2/neu or … evaluated in the first phase II clinical trial, including stage III-IV …
DCV pulsed with HER2/neu or … evaluated in the first phase II clinical trial, including stage III-IV …
Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity
… -negative tumor escape following adoptive cell therapy. … Moreover, OVA 257–264
peptide-pulsed FL-DCs were more … passed through a 70-μm filter and red blood cells were lysed …
peptide-pulsed FL-DCs were more … passed through a 70-μm filter and red blood cells were lysed …
Dendritic cells in cancer immunology and immunotherapy
… phase II study is ongoing 114 . In other clinical trials, intratumoural poly(I:C) derivatives in
combination with DC-based cancer … Regarding the use of whole tumour lysates for vaccination, …
combination with DC-based cancer … Regarding the use of whole tumour lysates for vaccination, …
Dendritic cells and cancer immunotherapy: The adjuvant effect
S Nava, D Lisini, S Frigerio, A Bersano - International Journal of …, 2021 - mdpi.com
… during phase II studies in prostate and breast cancer (NCT01560923; NCT01042535-phase
II… survival response compared to pulsed DCs with tumor lysate or galactosylceramide alone […
II… survival response compared to pulsed DCs with tumor lysate or galactosylceramide alone […
Antigen-loaded dendritic cells triggers a specific cytotoxic T lymphocytes immune response against hepatocellular carcinoma: in vitro study
… stimulated with whole cell tumor lysate pulsed-DCs showed … , which indicates whole cell
tumor lysate pulsed-DCs have … revealed that T cells stimulated with tumor lysate pulsed-DCs …
tumor lysate pulsed-DCs have … revealed that T cells stimulated with tumor lysate pulsed-DCs …
Dendritic cells loaded with allogeneic tumour cell lysate plus best supportive care versus best supportive care alone in patients with pleural mesothelioma as …
… cells per well) in the presence of tumour lysate (tumour cell to … dendritic cells pulsed with
allogeneic tumour cell lysate … with malignant peritoneal mesothelioma: a phase II clinical trial. …
allogeneic tumour cell lysate … with malignant peritoneal mesothelioma: a phase II clinical trial. …
Dendritic cells loaded with CD44+ CT‑26 colon cell lysate evoke potent antitumor immune responses
C Fu, N Zhou, Y Zhao, J Duan, H Xu… - Oncology …, 2019 - spandidos-publications.com
… study, dendritic cells (DCs) were pulsed with whole‑tumor cell lysates or total RNA of CD44+
colon cancer stem cells (… In addition, DCs pulsed with a tumor lysate derived from the mouse …
colon cancer stem cells (… In addition, DCs pulsed with a tumor lysate derived from the mouse …
Enhanced antitumor effect of cytotoxic T lymphocytes induced by dendritic cells pulsed with colorectal cancer cell lysate expressing α‑Gal epitopes
X Xing, Z Zou, C He, Z Hu, K Liang… - Oncology …, 2019 - spandidos-publications.com
… of tumor‑associated … study, α‑gal epitopes were synthesized on the CRC cell line SW620
to increase the immunogenicity of TAAs. DCs were pulsed with α‑gal‑expressing tumor lysate …
to increase the immunogenicity of TAAs. DCs were pulsed with α‑gal‑expressing tumor lysate …
Dendritic cells in pancreatic cancer immunotherapy: Vaccines and combination immunotherapies
… A Phase I/II clinical trial evaluated the efficacy of MUC1 peptide pulsed autologous DC …
Additionally, Adoptive immunotherapy with MUC1-DCs and MUC1-lymphocytes plus gemcitabine …
Additionally, Adoptive immunotherapy with MUC1-DCs and MUC1-lymphocytes plus gemcitabine …
Enhancing dendritic cell therapy in solid tumors with immunomodulating conventional treatment
RA Belderbos, JGJV Aerts, H Vroman - Molecular Therapy-Oncolytics, 2019 - cell.com
… function, and T-cell activation in the lymphnode. Checkpoint inhibitors … -tumor immune
response induced by dendritic cell (DC) therapy by blocking PD-(L)1 signaling in the tumor and …
response induced by dendritic cell (DC) therapy by blocking PD-(L)1 signaling in the tumor and …