Uveal melanoma: metastases

LT Xu, P Funchain, AA Tarhini, AD Singh - Clinical Ophthalmic Oncology …, 2019 - Springer
… combination” (dacarbazine, carmustine, cisplatin, and tamoxifen) [13]. … phase II study
investigating the combination of tremelimumab and interferon alpha-2b , eight patients with stage

[HTML][HTML] Nanotechnology-Based Drug Delivery Systems in the Transdermal Treatment of Melanoma

Z Saeidi, R Giti, M Rostami… - Advanced …, 2023 - ncbi.nlm.nih.gov
… , stage two is also a localized form but with a high risk of … 2 which stimulates T cell proliferation
and Interferon alpha; the … of dacarbazine, carmustine, cisplatin, and tamoxifen and the …

Systemic Therapy of Advanced Melanoma

A Lerner, V Furtado, D Sahni - Melanoma in Clinical Practice, 2021 - Springer
dacarbazine given alone or in combination with other chemotherapeutic agents or biological
modifiers such as cisplatin, vinblastine, vindesine, carmustine… as IL-2 or interferon-alpha 2B. …

Chimeric antigen receptor T-cell therapy for melanoma

A Razavi, M Keshavarz-Fathi, J Pawelek… - Expert Review of …, 2021 - Taylor & Francis
… to dacarbazine alone were about half compared to combinations of cisplatin, vinblastine or
vindesine, and dacarbazine … ’ combining carmustine, cisplatin, and dacarbazine caused deep …

[HTML][HTML] SIRT2 contributes to the resistance of melanoma cells to the multikinase inhibitor dasatinib

I Karwaciak, A Sałkowska, K Karaś… - Cancers, 2019 - mdpi.com
… , eg, cisplatin, vinblastine, and dacarbazine (CVD regiment) or cisplatin, dacarbazine,
carmustine, and tamoxifen (… The SIRT1 inhibitor EX-527 was tested in a phase II clinical study in …

Silica-based nanomaterials as drug delivery tools for skin cancer (melanoma) treatment

HT Trinh, S Mohanan, D Radhakrishnan, S Tiburcius… - Emergent …, 2021 - Springer
… drugs like dacarbazine/carmustine/cisplatin/tamoxifen in … lomustine/dacarbazine (BOLD)
and interferon alpha-2b in 2003 … -1 inhibitor) [77] or phase II nivolumab-with/without ipilimumab …

Targeting the IL-2 pathway for the treatment of mucosal melanoma

AC Mercurio, AB Maniar, AZ Wei… - Expert Opinion on …, 2022 - Taylor & Francis
Dacarbazine has been the only chemotherapy agent to … patients, and demonstrated that
temozolomide and cisplatin … to the phase II stage of the ARTISTRY clinical trial series of in …

[HTML][HTML] Melanoma biology and treatment: a review of novel regulated cell death-based approaches

M Hsieh, SK Hsu, TY Liu, CY Wu, CC Chiu - Cancer Cell International, 2024 - Springer
… , with a low response rate of 12.1–17.6% for dacarbazine [26,… In a phase II trial of temozolomide
(an oral alkylating agent) … drugs such as doxorubicin, cisplatin, and actinomycin-D, along …

[HTML][HTML] Targeting genome stability in melanoma—A new approach to an old field

M Osrodek, M Wozniak - International Journal of Molecular Sciences, 2021 - mdpi.com
melanoma, including platinum-based drugs (cisplatin, carboplatin) and alkylating agents (dacarbazine, …
The majority of ongoing phase 2 and 3 clinical trials test the combination of …

Principles and complications of chemotherapy

S Zahler, NG Ghazi, AD Singh - Clinical Ophthalmic Oncology: Basic …, 2019 - Springer
… been tried include dacarbazine, temozolomide, cisplatin, benda… interferon alpha-2b for
metastatic uveal melanoma. Eur J … Group experience in phase II advanced melanoma clinical trials…