The emerging role of the chondroitin sulfate proteoglycan family in neurodegenerative diseases

J Lin, M Duan, N Lin, W Zhao - Reviews in the Neurosciences, 2021 - degruyter.com
neurons and bind to specific receptors and neuronal cell adhesion molecules on the neuronal
cell … in turn causes an impairment of neuronal induction and the inability to generate new …

The effect of the sulfation patterns of dermatan and chondroitin sulfate from vertebrates and ascidians on their neuritogenic and neuroprotective properties

TB Medeiros, P Cosendey, DR Gerin… - International Journal of …, 2023 - Elsevier
caused by the progressive loss of the structure and function of neurons, leading to cell death
of Phallusia nigra dermatan sulfate (PnD2,6S) and compared it with two distinct structures of …

Chondroitin sulfate proteoglycans: key modulators of neuronal plasticity, long-term memory, neurodegenerative, and psychiatric disorders

X Yang - Reviews in the Neurosciences, 2020 - degruyter.com
chondroitin sulfate proteoglycans (CSPGs) are large groups of heterogenous proteoglycans
… post-transcriptionally modified by chondroitin sulfate glycosaminoglycans. CSPGs are the …

Study on the relationships between molecular weights of chondroitin sulfate oligosaccharides and Aβ-induced oxidative stress and the related mechanisms

N Zhao, J Meng, W Jiang, W Xu, C Liu, F Wang - Glycobiology, 2021 - academic.oup.com
… blocked Aβ-induced cell death as well. But different from the … injury of Aβ to neuron and
Aβ-induced neuroinflammation. … the best protective effects against Aβ injury to BV2 cells, which …

[HTML][HTML] Anticonvulsive effects of chondroitin sulfate on pilocarpine and pentylenetetrazole induced epileptogenesis in mice

S Singh, TG Singh, M Singh, A Najda… - Molecules, 2021 - mdpi.com
Chondroitin sulfate is a proteoglycan component of the … effects in rat brains by delaying
neuronal cell death induced by … with chondroitin sulfate showed a preventive effect in the …

[HTML][HTML] Neural tissue homeostasis and repair is regulated via CS and DS proteoglycan motifs

AJ Hayes, J Melrose - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
chondroitin sulfate (CS) and dermatan sulfate (DS)-proteoglycans (PGs) in neural biology,
heparan sulfate … -C binds to ephrin cell surface receptors resulting in induction of cell signaling …

[HTML][HTML] New insights on the role of chondroitin sulfate proteoglycans in neural stem cell–mediated repair in spinal cord injury

SM Hosseini, S Karimi-Abdolrezaee - Neural Regeneration …, 2025 - journals.lww.com
… excitotoxicity that culminate in neuronal and oligodendroglial cell death, demyelination, and
… To achieve a meaningful functional recovery after SCI, regeneration of new neurons and …

[HTML][HTML] Proteoglycan sulphation in the function of the mature central nervous system

JW Fawcett, JCF Kwok - Frontiers in Integrative Neuroscience, 2022 - frontiersin.org
… as chondroitin sulphate proteoglycans (CSPGs) and heparan … of the neurons: for instance
in embryonic hippocampal neurons, … then induced neurosphere formation, proliferation of cells

Proteoglycans and glycosaminoglycans in central nervous system injury

N Siddiqui, K Oshima… - … of Physiology-Cell …, 2022 - journals.physiology.org
Neuron-glial antigen 2 (NG2)/chondroitin sulfate … Many heparan sulfate-PGs and
chondroitin sulfate-PGs … It is during this chronic phase, once cell death driven by inflammation, …

Protective effects of chondroitin sulphate nano-selenium on a mouse model of Alzheimer's disease

D Ji, X Wu, D Li, P Liu, S Zhang, D Gao, F Gao… - International journal of …, 2020 - Elsevier
… in the ultrastructure of hippocampal neuron synapses of AD mice. … Chondroitin sulphate
proteoglycan (CSPG) is the most … of CS@Se were investigated on a D-gal and AlCl 3 induced AD …