Type III CRISPR-Cas systems: deciphering the most complex prokaryotic immune system

MV Kolesnik, I Fedorova, KA Karneyeva… - Biochemistry …, 2021 - Springer
… Here, we focus only on a putative evolutionary history of Class 1 CRISPR-Cas systems,
which includes Types I, III, and IV. These multisubunit complexes have similar architectures and …

RNA interference-based pesticides and antiviral agents: microbial overproduction systems for double-stranded RNA for applications in agriculture and aquaculture

S Hashiro, H Yasueda - Applied Sciences, 2022 - mdpi.com
… of shrimp toward Vibrio and other pathogenic bacteria. The target RNA was expressed in L.
… enhance the immune response of aquaculture organisms to pathogenic bacteria and viruses…

Acquired and innate immunity in prokaryotes define their evolutionary story

T Ito, M Okura, F Maruyama - DNA Traffic in the Environment, 2019 - Springer
immune systems (CRISPR-Cas systems) [46]. This chapter introduces a brief overview of the
principle of the innate immune systems in prokaryotes, … genes as a putative member of an …

Evolutionary and functional classification of the CARF domain superfamily, key sensors in prokaryotic antivirus defense

KS Makarova, A Timinskas, YI Wolf… - Nucleic acids …, 2020 - academic.oup.com
… are adaptive immunity systems that are present in nearly all archaea and ∼40% of bacteria
(… The CRISPR immune response consists of three stages, each mediated by a distinct subset …

[PDF][PDF] RNA interference-based characterization of Caspar, DREDD and FADD genes in immune signaling pathways of the red fl our beetle, Tribolium castaneum …

K Yokoi, W Ito, D Kato, K Miura - European Journal of Entomology, 2022 - biotaxa.org
… to their immune system by several species of microbes, including Gram-positive and -negative
bacteria as well as yeast. This contrasts with the Drosophila immune system in which …

Immune lag is a major cost of prokaryotic adaptive immunity during viral outbreaks

JL Weissman, EO Alseth, S Meaden… - … of the Royal …, 2021 - royalsocietypublishing.org
… Here, combining experiments and models, we show that a delayed immune response
which allows viruses to transiently redirect cellular resources to reproduction, which we call ‘…

CRISPR–Bacterial immune system

A Golubov - Genome Stability, 2021 - Elsevier
… defensive strategies in Archaea and Bacteria (reviewed in Ref. [2]) that can be referred to
as the multilayer prokaryotic immune system: the restriction-modification system (RMS), the …

Noncoding rna

E Desgranges, S Marzi, K Moreau, P Romby… - Microbiology …, 2019 - Am Soc Microbiol
… in many bacteria and in pathogenic bacteria such as … strain that encodes a putative
toxin-antitoxin system (see text … to escape from the host immune response. Among key regulators …

Adaptive Immunity Systems of Bacteria: Association with Self-Synthesizing Transposons, Polyfunctionality

TS Ilyina - Molecular Genetics, Microbiology and Virology, 2022 - Springer
… Such selective pressure provoked the production of various defense systems in bacteria
immune response. In this paper, we will consider the adaptive immunity systems of bacteria and …

Programmable RNA targeting with the single-protein CRISPR effector Cas7-11

A Özcan, R Krajeski, E Ioannidi, B Lee, A Gardner… - Nature, 2021 - nature.com
… E encompasses a single predicted effector protein that has been computationally characterized
as a fusion of four Cas7 group proteins and a putative Cas11 (Csm2)-like protein 3 . Here…