Neurodevelopmental outcomes at 42 months after thyroxine supplementation in infants below 28 weeks' gestation: a randomized controlled trial

SM Ng, MA Turner, AM Weindling - Thyroid, 2020 - liebertpub.com
cognitive functionstudy found that early replacement therapy with LT4 in doses of 5–10
μg/kg/day initiated in the second week of life was associated with improved long-term mental

[HTML][HTML] The impact of levothyroxine on cardiac function in older adults with mild subclinical hypothyroidism: a randomized clinical trial

B Gencer, E Moutzouri, MR Blum, M Feller… - The American journal of …, 2020 - Elsevier
… The TRUST trial (“Multi-Modal Effects of Thyroid Replacement for … study designs).7, 8, 9,
10, 11 Therefore, we aimed to assess the effect of thyroid hormone therapy on cardiac function

Effect of levothyroxine therapy on the development of depressive symptoms in older adults with subclinical hypothyroidism: an ancillary study of a randomized clinical …

L Wildisen, M Feller, C Del Giovane… - JAMA network …, 2021 - jamanetwork.com
… association task force on thyroid hormone replacement.  … In this ancillary study within a
randomized controlled trial … , levothyroxine therapy for 12 months had no clinical effect on …

L-thyroxine therapy for older adults with subclinical hypothyroidism and hypothyroid symptoms: secondary analysis of a randomized trial

M de Montmollin, M Feller, S Beglinger… - Annals of internal …, 2020 - acpjournals.org
Randomized clinical trials have shown that L-thyroxine does … the TRUST trial, which compared
L-thyroxine versus placebo … whether L-thyroxine improved hypothyroid symptoms among …

Association between levothyroxine treatment and thyroid-related symptoms among adults aged 80 years and older with subclinical hypothyroidism

SP Mooijaart, RS Du Puy, DJ Stott, PM Kearney… - Jama, 2019 - jamanetwork.com
randomization by age in the Thyroid Hormone Replacement … ]) or in executive cognitive
function measured with the Letter … blinded randomized clinical trials that examined the effects of …

Association of thyroid dysfunction with cognitive function: an individual participant data analysis

…, S Trompet, Thyroid Studies Collaboration - JAMA internal …, 2021 - jamanetwork.com
… or thyroid hormone replacementrandomized clinical trial on levothyroxine treatment for
subclinical hypothyroidism also did not provide evidence for improvement of cognitive function

[HTML][HTML] Does Hormone Supplementation With Levothyroxine Improve Hypothyroid Impaired Cognitive Dysfunction?

D Uma, R Rabbani, JH Lee, DR Gavini, PH Shah… - Cureus, 2021 - ncbi.nlm.nih.gov
… for clinical trials, the New Castle-Ottawa questionnaire for observational … cognitive impairment.
We also reviewed and analyzed the effect of thyroid hormone replacement on cognitive

Effect of thyroid hormone therapy on fatigability in older adults with subclinical hypothyroidism: a nested study within a randomized placebo-controlled trial

MJ Stuber, E Moutzouri, M Feller… - The Journals of …, 2020 - academic.oup.com
… from randomized controlled trial investigating the effect of levothyroxine (LT4) replacement
on … of LT4 treatment on both physical and mental fatigability in older subjects with SHypo. …

[PDF][PDF] Effect of Levothyroxine Replacement on Cognitive Function Impairment in a Sample of Egyptian Population with Subclinical Hypothyroidism

SSHE Dina, AMNN Adly - 2022 - scholar.archive.org
study aimed to investigate the effect of levothyroxine replacement on cognitive impairment in
… This comes in line with a meta-analysis study of 12 randomized controlled trials on 940 par…

Optimal thyroid hormone replacement

J Jonklaas - Endocrine reviews, 2022 - academic.oup.com
trial of combination therapy with levothyroxine and liothyronine. This is not supported by the
majority of randomized clinical trials, … , QOL, or cognitive function associated with the different …