… atrial fibrillation and ischemic stroke genome-wide … of ZFHX3 in the atria may be involved
in arrhythmogenesis processes and, subsequently, variants on 16q22 locus may be associated …

… on chromosome 16q22 (in ZFHX3) were not associated with … [1] AF increases the incidence
of ischemic stroke, heart failure… and common or rare variants associated with AF have been …

… variants and the risk of ischemic stroke, Malik’s group studied PITX2 and ZFHX3 genes
and found a significant association … 4q25 [PITX2], 16q22 [ZFHX3]) and AF recurrence after …

… a strong association between two sequence variants (PITX2, … gene on chromosome 16q22
significantly associated with AF … , and rs2106261 in ZFHX3) were associated with methylation …

… ZFHX3 as the causative gene at the 16q22 locus for AF, and cardiac abnormalities caused
by loss of cardiac Zfhx3 are due to atrial-… in Zfhx3 deficient atria many genes associated with …

… In the prospective Malmö Diet and Cancer Study, incident ischemic stroke was associated …
variant rs2106216 at the ZFHX3 locus on chromosome 16q22 was independently associated …

… Importantly, risk variants associated to KCNN3, ZFHX3 and … those at transcriptional level by
ZFHX3 we investigated in any … , JC Variants in ZFHX3 are associated with atrial fibrillation in …

… : The ZFHX3 gene (16q22) is the second most highly associated gene with atrial fibrillation
(AF) … We hypothesized that ZFHX3 is associated with extra-pulmonary vein (PV) triggers, left …

… a strong association between AF and two sequence variants … the ZFHX3 SNV rs2106261
minor allele was associated with … at 23% increased risk for ischemic stroke. A 2018 study by …

… in correspondence with ischemic stroke in the METASTROKE … wide association studies for
AF identified a new locus: ZFHX3. … Located on chromosome 16q22, ZFHX3 is associated with …