Modern kinetics and mechanism of protein folding: A retrospective

WA Eaton - The Journal of Physical Chemistry B, 2021 - ACS Publications
… The concept of internal friction in protein folding kinetics was motivated by our work on the
conformational changes in myoglobin following photodissociation of the carbon monoxide …

The protein folding problem: the role of theory

R Nassar, GL Dignon, RM Razban, KA Dill - Journal of molecular biology, 2021 - Elsevier
… astronomically large conformational spaces of non-native states of proteins, the equilibrium
structures they attained, and the kinetics of searching those spaces and finding native states. …

[HTML][HTML] Downhill, ultrafast and fast folding proteins revised

M Banach, K Stapor, L Konieczny, P Fabian… - International Journal of …, 2020 - mdpi.com
protein folding problem differentiates the protein folding process with respect to the duration
of this process. The current structure … with more complex kinetics. The low RD value for the …

Protein structure optimization using improved simulated annealing algorithm on a three-dimensional AB off-lattice model

L Zhang, H Ma, W Qian, H Li - Computational Biology and Chemistry, 2020 - Elsevier
… algorithm for protein structure optimization based on a three-dimensional AB off-lattice model.
… In this section, comprehensive simulations for protein folding structure were carried out on …

Protein folding from heterogeneous unfolded state revealed by time-resolved X-ray solution scattering

TW Kim, SJ Lee, J Jo, JG Kim, H Ki… - Proceedings of the …, 2020 - National Acad Sciences
Protein undergoes a folding pathway to find a three-dimensional structure that expresses its
… , which can potentially alter the kinetic behavior in the protein folding due to the possibility of …

Ultrafast folding kinetics of WW domains reveal how the amino acid sequence determines the speed limit to protein folding

M Szczepaniak, M Iglesias-Bexiga… - Proceedings of the …, 2019 - National Acad Sciences
… is universal or depends on the protein’s chemical properties. We apply ultrafast kinetic
methods to investigate five proteins that share the simplest all-β fold but have different amino acid …

Structure folding of RNA kissing complexes in salt solutions: predicting 3D structure, stability, and folding pathway

L Jin, YL Tan, Y Wu, X Wang, YZ Shi, ZJ Tan - RNA, 2019 - rnajournal.cshlp.org
… -grained model with an implicit structure-based electrostatic potential to predict three-dimensional
(3D) structures … , our model shows great reliability in predicting 3D structures from their …

Protein folding problem: enigma, paradox, solution

AV Finkelstein, NS Bogatyreva, DN Ivankov… - Biophysical …, 2022 - Springer
… The ability of protein chains to spontaneously form their three-dimensional structures is a …
of protein folding kinetics, including folding landscapes and funnels, free energy barriers at the …

[图书][B] Protein folding: An introduction

CM Gomes, PFN Faísca, CM Gomes, PFN Faísca - 2019 - Springer
Proteins fold into a diversity of three-dimensional structures with diverse topologies and
well-defined structural … the thermodynamic and kinetic grounds of the folding process, but for now…

[HTML][HTML] Is protein folding a thermodynamically unfavorable, active, energy-dependent process?

I Sorokina, AR Mushegian, EV Koonin - International journal of molecular …, 2022 - mdpi.com
models can be formulated, in general terms, as thermodynamic vs. kinetic control of protein
folding. … G among the kinetically accessible structures. However, this approach to the study of …