… of treatment options for opioid misuse and addiction in adults and for … of chronic pain, poor
translation of preclinical data and … the potential utility of a concerted multiomic approach for …

… We then propose a reverse translational approach, whose … and the community-reinforcement
approach. These reverse-… potential predictive validity for identifying new treatments. …

… potential translation to novel clinical settings. Here, we review recent studies using these
approaches … be a significant correspondence between actual and predicted values (9). Clinical …

… In this approach, the rewarding value of alcohol is measured … in clinical trials to test the abuse
potential of new drugs. However, CPP … the potential role of neuroimaging in understanding …

… This translational science contributes to the understanding of … result in misuse and related
outcomes such as addiction. … the potentially fatal cardiac arrhythmia torsades de pointes (45). …

… predictive potential and slow down the development of PPPM and consequently modern
healthcare. Therefore, it is the common goal of PPPM and translational … ’ prediction power that is …

… We argue that the integration of computational approaches with neuroscience techniques in
… that are necessary for understanding human psychopathologies, such as addiction (Figure 1…

… pharmacology, engagement of translational approaches, … treatment options and translational
psychopharmacology for … patients and point to the potential value, in general, of genotyping …

… importance of metabolomics as a powerful approach for biomarker discovery and its potential
… ) and peripheral tissues/biofluids with translational value (eg, blood, urine and hair). As our …

… In these ways, the use of linked cross-species procedures is predicted to accelerate our
mechanistic understanding of the choice to use abused substances and the development of …