Role of the AMPK/SIRT1 pathway in non‑alcoholic fatty liver disease
P Anggreini, H Kuncoro… - Molecular medicine …, 2023 - spandidos-publications.com
… to summarize the role of AMPK and SIRT1 in NAFLD, … of AMPK and SIRT1 activators on
NAFLD. Articles were obtained from the PubMed database identified using the key words ‘SIRT1 …
NAFLD. Articles were obtained from the PubMed database identified using the key words ‘SIRT1 …
Pharmacological perspectives and clinical benefits of SIRT1 and AMPK activators and inhibitors in inflammatory and oxidative stress in the liver
L Njeka Wojnarová - 2022 - dspace.cuni.cz
… (SIRT1) and AMP-activated protein kinase (AMPK), can effectively attenuate acute liver injury.
Although SIRT1 and AMPK … evidence for a mutual SIRT1/AMPK signaling mechanism and …
Although SIRT1 and AMPK … evidence for a mutual SIRT1/AMPK signaling mechanism and …
SIRT1 antagonizes oxidative stress in diabetic vascular complication
… Importantly, AMPK and SIRT1 both regulate each other and have similar effects on various
cellular processes such as cell metabolism, DNA repair, mitochondrial function, and cell …
cellular processes such as cell metabolism, DNA repair, mitochondrial function, and cell …
Epigenetic Changes in Aging: The Contribution of SIRT1 to Longevity
DK Alves-Fernandes, MG Jasiulionis - Cellular and Molecular Aspects of …, 2024 - Springer
… turn, AMPK promotes NAD+ synthesis, which is required to SIRT1 activity [123]. The activation
of AMPK enhances SIRT1 … 1α (PGC1α), another target of SIRT1 [124]. PGC1α serves as a …
of AMPK enhances SIRT1 … 1α (PGC1α), another target of SIRT1 [124]. PGC1α serves as a …
Inverse correlation between the expression of AMPK/SIRT1 and NAMPT in psoriatic skin: A pilot study
F D'Amico, G Costantino, L Salvatorelli… - Advances in Medical …, 2022 - Elsevier
… Given the involvement of SIRT1 in inhibiting proliferation and … dysregulatory aspects of SIRT1,
NAMPT and AMPK in psoriasis… , the protein expression of SIRT1, AMPK (and pAMPK) and …
NAMPT and AMPK in psoriasis… , the protein expression of SIRT1, AMPK (and pAMPK) and …
The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1α signalling pathway
X Yang, Q Liu, Y Li, Q Tang, T Wu, L Chen, S Pu… - Adipocyte, 2020 - Taylor & Francis
… activated protein kinase (AMPK) – silent information regulator 1 (Sirt1) – peroxisome proliferator…
that Cana increased AMPK phosphorylation and the expression of Sirt1 and Pgc-1α. The …
that Cana increased AMPK phosphorylation and the expression of Sirt1 and Pgc-1α. The …
Acacetin ameliorates cardiac hypertrophy by activating Sirt1/AMPK/PGC-1α pathway
YK Cui, YX Hong, WY Wu, WM Han, Y Wu, C Wu… - European Journal of …, 2022 - Elsevier
… hypertrophy via Sirt1-mediated activation of AMPK/PGC-… Sirt1/AMPK participates in
antagonization of acacetin against cardiomyocyte hypertrophy. AMP-activated protein kinase (AMPK) …
antagonization of acacetin against cardiomyocyte hypertrophy. AMP-activated protein kinase (AMPK) …
[HTML][HTML] Short-term moderate caloric restriction in a high-fat diet alleviates obesity via AMPK/SIRT1 signaling in white adipocytes and liver
S Zhang, S Sun, X Wei, M Zhang, Y Chen… - Food & nutrition …, 2022 - ncbi.nlm.nih.gov
… AMPK and SIRT1 are long-term partners (31). They have similar effects on diverse
processes, such as cellular fuel metabolism, inflammation, and mitochondrial function. …
processes, such as cellular fuel metabolism, inflammation, and mitochondrial function. …
Advanced glycation end products induced mitochondrial dysfunction of chondrocytes through repression of ampkα-SIRT1-PGC-1α pathway
Q Yang, Y Shi, T Jin, B Duan, S Wu - Pharmacology, 2022 - karger.com
… AMP-activated protein kinase (AMPK), sirtuin 1 (SIRT1), and its downstream target … of
AMPKα/SIRT1/PGC-1α. Methods: We knocked down or overexpressed AMPKα, SIRT1, and PGC-…
AMPKα/SIRT1/PGC-1α. Methods: We knocked down or overexpressed AMPKα, SIRT1, and PGC-…
The mixed blessing of AMPK signaling in Cancer treatments
… SIRT1 inhibitor at a dosage that reduces SIRT1 bioavailability to 10% of its baseline. We then
examined the resulting AMPK … indirect AMPK inhibition via the inhibition of SIRT1, which is …
examined the resulting AMPK … indirect AMPK inhibition via the inhibition of SIRT1, which is …