ATM protein kinase: old and new implications in neuronal pathways and brain circuitry
L Pizzamiglio, E Focchi, F Antonucci - Cells, 2020 - mdpi.com
… of vesicles playing complementary roles: ATM with excitatory (VGLUT1+) vesicles and ATR
with inhibitory … and in controlling neuronal function and behaviour. Considering the crucial …
with inhibitory … and in controlling neuronal function and behaviour. Considering the crucial …
ATM rules neurodevelopment and glutamatergic transmission in the hippocampus but not in the cortex
E Focchi, C Cambria, L Pizzamiglio, L Murru… - Cell Death & …, 2022 - nature.com
… inhibitor Fluoxetine (Fluox), we demonstrate that ATM … as cytoplasmic vesicles membrane
and transport vesicles membrane (… not experience any hyperexcitability behaviour after kainate …
and transport vesicles membrane (… not experience any hyperexcitability behaviour after kainate …
ATR regulates neuronal activity by modulating presynaptic firing
M Kirtay, J Sell, C Marx, H Haselmann… - Nature …, 2021 - nature.com
… specific ATR deletion in inhibitory and excitatory postmitotic … , whether ATR directly modulates
presynaptic vesicle behaviors or … Although the expression of ATR and ATM seemed to be …
presynaptic vesicle behaviors or … Although the expression of ATR and ATM seemed to be …
New views of the DNA repair protein ataxia–telangiectasia mutated in central neurons: Contribution in synaptic dysfunctions of neurodevelopmental and …
S Briguglio, C Cambria, E Albizzati, E Marcello… - Cells, 2023 - mdpi.com
… the great importance of ATM in neuronal functions and in synaptic vesicle recycling [29]. A
… ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle …
… ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle …
ATM loss disrupts the autophagy-lysosomal pathway
… synaptic vesicle binding proteins. Extending this observation, we found that ATM inhibition
… affected other key proteins, we assessed the behavior of SLC2A4, a glucose transporter […
… affected other key proteins, we assessed the behavior of SLC2A4, a glucose transporter […
The ataxia-telangiectasia disease protein ATM controls vesicular protein secretion via CHGA and microtubule dynamics via CRMP5
M Reichlmeir, RP Duecker, H Roehrich, J Key… - bioRxiv, 2024 - biorxiv.org
… and phosphorylome - both direct ATM/ATR-phosphopeptides and … with HALT phosphatase
inhibitors (Thermo Fisher Scientific) … kinase targets of ATM, we performed two complementary …
inhibitors (Thermo Fisher Scientific) … kinase targets of ATM, we performed two complementary …
[PDF][PDF] DNA damage and transcriptional regulation in ipsC-derived neurons from Ataxia telangiectasia patients
D Lecis, KH Chrzanowska, D Delia - core.ac.uk
… regulate endocytosis of synaptic vesicles, as opposite to ATR which associates with inhibitory
… ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle …
… ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle …
DNA damage and transcriptional regulation in iPSC-derived neurons from Ataxia Telangiectasia patients
A Corti, R Sota, M Dugo, RA Calogero, B Terragni… - Scientific Reports, 2019 - nature.com
… ATM was shown to segregate with and regulate endocytosis of synaptic vesicles, as opposite
to ATR which associates with inhibitory … transcriptional rescue behavior between WT and …
to ATR which associates with inhibitory … transcriptional rescue behavior between WT and …
In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While …
M Reichlmeir, J Canet-Pons, G Koepf, W Nurieva… - Cells, 2023 - mdpi.com
… inositol lipids, while ATM and its homolog ATR were reported to … excitation, while ATR was
implicated in a complementary … of synaptic vesicles not only for excitatory but also for inhibitory …
implicated in a complementary … of synaptic vesicles not only for excitatory but also for inhibitory …
Versatility of the Mec1ATM/ATR signaling network in mediating resistance to replication, genotoxic, and proteotoxic stresses
I Corcoles-Saez, K Dong, RS Cha - Current genetics, 2019 - Springer
… of the human ATM and MEC1, the budding yeast ATM/ATR, were shown … Further analyses
unveiled that ATM and Mec1 promote … the key findings and discuss ATM/ATR as a multifaceted …
unveiled that ATM and Mec1 promote … the key findings and discuss ATM/ATR as a multifaceted …