Epigenetics of male infertility: the role of DNA methylation

JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
imprinted gene H19 in sperm DNAs from infertile males with … testicular genome have been
detected between obstructiveaberrant DNA methylation in spermatozoa is linked to defective …

Whole-genome methylation analysis of testicular germ cells from cryptozoospermic men points to recurrent and functionally relevant DNA methylation changes

S Di Persio, E Leitão, M Wöste, T Tekath, JF Cremers… - Clinical …, 2021 - Springer
… patterns, in particular in imprinted genes. In a recent … patients might carry aberrant DNA
methylation, we compared … germ cells from patients with obstructive azoospermia (CTR, n = 24) …

The role of DNA methylation in human spermatogenesis

I Shafran - 2022 - repozitorij.mef.unizg.hr
… of male infertility, can be due to obstructive or non-obstructive … on the abnormal DNA
methylation in imprinted genes associated … MEST DNA aberrant methylation, a maternally …

[PDF][PDF] DNA METHYLATION USING IMPRINTING SNRPNGENE AND EFFECT ON ARRESTED SPERMATOGENESIS IN IRAQI OLIGOSPERMIA PATIENTS

HK Al-Qazzaz, SJ Al-Awadi - researchgate.net
male infertility and for molecular study using specific primer of … in genetic imprinting and
thereby may result in aberrant … 1: DNA methylation at DMRs of imprinting genes as predicted …

The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis

E Leitão, S Di Persio, S Laurentino, M Wöste… - Clinical …, 2020 - Springer
aberrant DNA methylation of imprinted genes (eg MEST and H19) in sperm of oligozoospermic
men… previously shown to be expressed in germ cells and not in testicular somatic cells [22…

A DNA methylation perspective on infertility

G Shacfe, R Turko, HH Syed, I Masoud, Y Tahmaz… - Genes, 2023 - mdpi.com
… Indeed, aberrant DNA methylation has been widely … to abnormal expression of imprinting
and non-imprinting genes. … In this context, males with non-obstructive azoospermia, …

[PDF][PDF] Impact of DNA Methylation and Gene Expression of H19, SNRPN and LINE-1 Genes on Oligospermia

HK Al-Qazzaz, SJ Al-Awadi - Iraqi journal of biotechnology, 2022 - iasj.net
Aberrant DNA methylation at imprinted genes in testicular sperm retrieved from men with
obstructive azoospermia and undergoing vasectomy reversal, Society for Reproduction and …

Decreased expression of DNA methyltransferases in the testes of patients with non-obstructive azoospermia leads to changes in global DNA methylation levels

F Uysal, G Akkoyunlu, S Ozturk - Reproduction, Fertility and …, 2019 - CSIRO Publishing
… well as global DNA methylation profiles in testicular biopsy samples obtained from men with
… abnormal DNA methylation of development-related or imprinting genes most likely leads to …

Role of genetics and epigenetics in male infertility

S Gunes, SC Esteves - Andrologia, 2021 - Wiley Online Library
… The second most common genetic aberration causing male … overall successful in retrieving
testicular spermatozoa and achieving … sperm DNA methylation aberrations of imprinted genes

Male aging and obesity effects on sperm methylome and consequences for the next generation

RSK Potabattula - 2019 - opus.bibliothek.uni-wuerzburg.de
male aging significantly increased the DNA methylation levels … Epimutations, which are
aberrantly methylated CpG sites, … elements and imprinted genes respectively in sperm, and also …