The untranslated regions of mRNAs in cancer
SL Schuster, AC Hsieh - Trends in cancer, 2019 - cell.com
… present novel therapeutic opportunities in cancer. The 5′ and 3′ untranslated regions (UTRs)
regulate crucial aspects of post-transcriptional gene regulation that are necessary for …
regulate crucial aspects of post-transcriptional gene regulation that are necessary for …
[HTML][HTML] Role of noncoding RNAs and untranslated regions in cancer: A review
Y Zhang, M Yang, S Yang, F Hong - Medicine, 2022 - journals.lww.com
… Inflammation can deliver growth signals, leading to the … its mRNA 3’-UTR. The reduction
of DDX5 facilitated the expression of c-Myc and hepatic cancer stem cell-like genes, aberrant …
of DDX5 facilitated the expression of c-Myc and hepatic cancer stem cell-like genes, aberrant …
The regulatory role of non-coding RNAs on programmed cell death four in inflammation and cancer
M Zhao, N Zhu, F Hao, Y Song, Z Wang, Y Ni… - Frontiers in …, 2019 - frontiersin.org
… 3′-untranslated region (UTR) to promote tumor proliferation, migration, and invasion in colon,
breast, and bladder carcinoma… In brief, aberrant PDCD4 expression levels are associated …
breast, and bladder carcinoma… In brief, aberrant PDCD4 expression levels are associated …
mRNA post-transcriptional regulation by AU-rich element-binding proteins in liver inflammation and cancer
D Dolicka, C Sobolewski, M Correia de Sousa… - International journal of …, 2020 - mdpi.com
… tumor suppressors, they exhibit important regulatory functions in inflammation and cancer
… Regarding liver cancers, our discussion focuses mostly on HCC since the role of AUBPs on …
… Regarding liver cancers, our discussion focuses mostly on HCC since the role of AUBPs on …
Non-coding RNA-based regulation of inflammation
… of inflammation is involved in pathogenesis of different diseases such as diabetes mellitus,
cardiovascular diseases and even, cancer. … in inflammation regulation and resolution. Pro-…
cardiovascular diseases and even, cancer. … in inflammation regulation and resolution. Pro-…
RNA-biology ruling cancer progression? Focus on 3′ UTRs and splicing
AE Erson-Bensan - Cancer and Metastasis Reviews, 2020 - Springer
… that represent both worlds; 3′ untranslated regions (3′UTRs), … biological processes
including inflammatory response [13], … that aberrant splicing is widespread in cancers (aberrant …
including inflammatory response [13], … that aberrant splicing is widespread in cancers (aberrant …
Circular RNAs are a novel type of non-coding RNAs in ROS regulation, cardiovascular metabolic inflammations and cancers
… in ROS regulation and vascular inflammation-associated … as a functionless byproducts of
aberrant RNA splicing and thus … their target messenger RNA (mRNA) at 3’ untranslated region (…
aberrant RNA splicing and thus … their target messenger RNA (mRNA) at 3’ untranslated region (…
Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs
Y Uchida, T Chiba, R Kurimoto… - The journal of …, 2019 - academic.oup.com
… regulation, RBPs recognize and directly bind to cis-regulatory elements in 3′ untranslated
region of mRNAs … Aberrant expression of inflammatory cytokines causes severe autoimmune …
region of mRNAs … Aberrant expression of inflammatory cytokines causes severe autoimmune …
Common gene variants within 3′‐untranslated regions as modulators of multiple myeloma risk and survival
… -inflammatory cytokine. In macrophages, it inhibits the expression of inflammatory cytokines
(… of the pro-inflammatory cytokines IL-1β and IL-6 that are aberrantly expressed by MM cells. …
(… of the pro-inflammatory cytokines IL-1β and IL-6 that are aberrantly expressed by MM cells. …
Aberrant post-transcriptional regulation of protein expression in the development of chronic obstructive pulmonary disease
N Aloufi, A Alluli, DH Eidelman, CJ Baglole - International Journal of …, 2021 - mdpi.com
… deadenylation of tumor necrosis factor alpha (TNF-α) mRNA and its … ) in the 3’-untranslated
region (UTR)—these mRNA typically … , inflammation, and fibrosis [63,64,65,66,67,68,69,70]. …
region (UTR)—these mRNA typically … , inflammation, and fibrosis [63,64,65,66,67,68,69,70]. …