… Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, IL-23A (p19)
and IL… as Schirmer I Test, break up time (BUT) and corneal fluorescent staining (CFS) (231). …

… binding affinity to IL-23 and bioactivity in whole blood. … anti-IL23 antibodies-treated groups
after subtraction of day 0 level. … Cell intercalation with natural abundance iridium was done …

… The p19 subunit is a 19K mw subunit that is linked by … Biologically active IL-23 requires both
subunits to be synthesized … There are a variety of gut pathogens that evoke a significant IL23 …

… pathogenesis of PsA is IL23. IL-23 is a heterodimer composed of two subunits p19 and p40
… Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in …

… Considering the accumulating evidence on the pathogenic role of IL23, we generated
106 … expression of the interleukin (IL)23 subunit p19, but low levels of bioactive IL23 432 …

… inflammation and reduced fibrosis by blocking interleukin-… detected in IL-23−/− mice but
not in mice lacking the IL-12 … inhibition of IL-23 via binding to its p19 subunit, demonstrated …

… Interleukin (IL)-23 is a heterodimeric pro-inflammatory … to our knowledge, that IL-23 gene
expression was significantly … c concentrations as compared to those with normal or low LDL-c …

… IL23/IL17 axis are currently approved and marketed (Fig. 3). … , IL-12 and IL-23 were found
to be abundantly expressed by … of SpA, blockade of IL-17A, but not of TNF-α, reduced clinical …

… Recently, interleukin-23 (IL-23) has been confirmed as … characterisation of a novel anti-IL-23
p19-specific SDA that has … , such as MMP3 and MMP12 are abundant in these tissues 38,39 …

… with synoviocytes but not with skin fibroblasts decreased IL-23 … This was coherent with
the low levels of bioactive IL-23 … RANKL and interleukin-1. Am J Pathol. 2005;167(1):141–9. …