[PDF][PDF] Utilisation of CFTR orthologues to evaluate new therapies for cystic fibrosis

D Ng - 2022 - research-information.bris.ac.uk
secreted antimicrobial activity in airways of neonatal CF pigs, with the former caused by
tethered mucus to submucosal gland … - and fluid secretion is vital for nutrient digestion. In CF, …

Animal Models and Their Role in Understanding the Pathophysiology of Cystic Fibrosis–Associated Gastrointestinal Lesions

KN Gibson-Corley, JF Engelhardt - Annual Review of Pathology …, 2021 - annualreviews.org
… symptoms, such as airway clearance techniques, antibiotics, … and include submucosal
edema and gastric gland dilation. … patients age when acinar dilation with secretory material is …

[PDF][PDF] Recent advances in vasoactive intestinal peptide physiology

M Iwasaki, Y Akiba, JD Kaunitz - pathophysiology, 2019 - pdfs.semanticscholar.org
… VIP is mainly localized in the myenteric and submucosal … – secretion via a CFTR-dependent
pathway46. In the ileum and … also stimulate amylase secretion from pancreatic acini of rat …

[HTML][HTML] Mucus Matters: Mucociliary Physiology in Chronic Lung Diseases

JEP Lever - 2021 - search.proquest.com
airways and is not produced by submucosal glands 2,24. … Mucus bundles float on the airway
surface liquid (ASL) and are … of the organ, and its natural acini or lobules deposited in the …

Cystic Fibrosis Immune Defect and Intestinal Disease Pathogenesis

C Scull - 2023 - search.proquest.com
… The loss of CFTR function inhibits healthy acinar cell functions and results in pancreatic …
Due to rats having submucosal glands throughout the trachea, they are better models for airway

Nonspecific and specific factors of bronchopulmonary tissue in inflammatory pathology

KF Muinovna, IJ Mardonovich - Journal Of Biomedicine And Practice, 2023 - tadqiqot.uz
… «Substance P stimulates human airway submucosal gland secretion mainly via a CFTR
dependent process» // The … «Fluid secretion by submucosal glands of the tracheobronchial …

Restoring airway function in muco-obstructive diseases by modulating TMEM16A and SLC26A9

R Martins Centeio - 2023 - epub.uni-regensburg.de
… , larger airways (diameter > 2 mm), submucosal glands (SMG… acinar cells of salivary and
pancreatic glands, airway smooth … cAMP-mediated (CFTRdependent) Cl- secretion, was firstly …

Modulation of TMEM16 proteins: a novel therapeutic approach to Cystic Fibrosis therapy

R Benedetto - 2019 - epub.uni-regensburg.de
… to bypass defective CFTR dependent Cl- secretion. In the … of the distal airways and submucosal
glands is the main cause … pancreatic and salivary gland acini or in airway epithelial cells, …