Adenosine receptor A2B negatively regulates cell migration in ovarian carcinoma cells

AR Campos-Contreras, A González-Gallardo… - International Journal of …, 2022 - mdpi.com
… the characterization of A2B receptor in particular cell lines. … activation of A2BR contributes
to ovarian cancer-derived cell … by cell proliferation, we evaluated if A2BR regulated cell viability…

A2B Adenosine Receptor and Cancer

ZG Gao, KA Jacobson - International journal of molecular sciences, 2019 - mdpi.com
activation of the P2Y 1 receptor (P2Y 1 R) subtype [1,2], whereas adenosine induces cancer
cell proliferation and growth … -small cell lung cancer, breast cancer and ovarian cancer. A 2B …

Adenosine receptor A2b confers ovarian cancer survival and PARP inhibitor resistance through IL‐6‐STAT3 signalling

L Chi, L Huan, C Zhang, H Wang… - Journal of Cellular and …, 2023 - Wiley Online Library
… in ovarian cancer cells, we examined the cell growth and … signalling regulates cell survival
and proliferation by activating … upregulated A 2B senses adenosine signal and activates IL-6…

[HTML][HTML] Blockade of adenosine A2b receptor reduces tumor growth and migration in renal cell carcinoma

Y Yi, Y Zhou, X Chu, X Zheng, D Fei, J Lei, H Qi… - … of Cancer, 2020 - ncbi.nlm.nih.gov
… , prostate, ovarian carcinoma, adenosine A2b receptor is … adenosine receptors, which suggests
that it may play a role in … CREB activation by PKA, thereby increasing cell proliferation 31 …

Adenosine and adenosine receptors in colorectal cancer

F Hajizadeh, A Masjedi, SH Asl, FK Kiani… - International …, 2020 - Elsevier
… as breast cancer, colon cancer, ovarian cancer, melanoma, … Whereas, A2A and A2B adenosine
receptors by activating the Gs … has a critical role in adenosine-mediated tumor cell growth

Adenosine analogues as opposite modulators of the cisplatin resistance of ovarian cancer cells

K Bednarska-Szczepaniak… - Anti-Cancer Agents …, 2019 - ingentaconnect.com
activation may support the growth and chemotaxis of tumour … for adenosine receptors on
cisplatin toxicity to ovarian cancer … Ligands for A2B or A3 receptors have also been examined as …

Adenosine receptor A2B antagonist inhibits the metastasis of gastric cancer cells and enhances the efficacy of cisplatin

H Wang, F Tan, Y Xu, Y Ma, Y Li… - Technology in Cancer …, 2023 - journals.sagepub.com
cell carcinoma have demonstrated that ADORA2B regulates cell proliferation by activating
HIF-… (SKOV-3), and conversely, an inducer can reduce the migration of ovarian cancer cells, 2 …

Adenosine interaction with adenosine receptor A2a promotes gastric cancer metastasis by enhancing PI3K–AKT–mTOR signaling

L Shi, Z Wu, J Miao, S Du, S Ai, E Xu… - … biology of the cell, 2019 - Am Soc Cell Biol
… that adenosine can regulate the … adenosine in a hypoxic TME can activate the PI3K–AKT–mTOR
signaling pathway by binding to A2aR, and then promote EMT and enhance cancer cell

Therapeutic potency of pharmacological adenosine receptors agonist/antagonist on cancer cell apoptosis in tumor microenvironment, current status, and perspectives

A Soleimani, A Bahreyni, MK Roshan… - Journal of cellular …, 2019 - Wiley Online Library
… (A1, A2A, A2B, and A3) on tumor cells. TME: … on the growth of ovarian cancer cells is
due to the activation of caspase-3 … , adenosine decreases cell proliferation and arrests cell-cycle

Therapeutic potentials of A2B adenosine receptor ligands: current status and perspectives

B Chandrasekaran, S Samarneh… - Current …, 2019 - ingentaconnect.com
… kinases (ERK1/2) which has a crucial role in the cell growth, … , A2B ARregulated cellular
proliferation via the activation of … AR in the initiation of the apoptosis in ovarian cancer cells. …