[HTML][HTML] DAF-16/FoxO in Caenorhabditis elegans and Its Role in Metabolic Remodeling

A Zečić, BP Braeckman - Cells, 2020 - mdpi.com
long-lived and supports the idea that daf-2 mutants could potentially rely on the heterochronically
activated dauer survival program for their longevity … levels of reactive oxygen species […

Hypotaurine promotes longevity and stress tolerance via the stress response factors DAF-16/FOXO and SKN-1/NRF2 in Caenorhabditis elegans

QL Wan, X Fu, X Meng, Z Luo, W Dai, J Yang… - Food & function, 2020 - pubs.rsc.org
… elegans by activating DAF-16/FOXO. … Reactive oxygen species (ROS), as a byproduct of
normal metabolism, … failed to extend the lifespan of the long-lived mitochondrial dysfunction isp-…

[HTML][HTML] Uric acid induces stress resistance and extends the life span through activating the stress response factor DAF-16/FOXO and SKN-1/NRF2

QL Wan, X Fu, W Dai, J Yang, Z Luo, X Meng… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… factors DAF-16/FOXO, SKN-1/NRF2 and HSF-1 contribute to … Reactive oxygen species (ROS)
are generated as a … extend the life span of either the long-lived mitochondrial dysfunctional …

[HTML][HTML] Genes and longevity of lifespan

MN Bin-Jumah, MS Nadeem, SJ Gilani… - International Journal of …, 2022 - mdpi.com
… the regulation of lifespan such as DAF-16/FOXO (forkhead box … Oxidative stress typically
caused by reactive oxygen species (… Activation of DAF-16/FOXO by low IIS triggers the complex …

Pioglitazone Hydrochloride Extends the Lifespan of Caenorhabditis elegans by Activating DAF16/FOXO‐ and SKN‐1/NRF2‐Related Signaling Pathways

W Jia, C Wang, J Zheng, Y Li, C Yang… - … Cellular Longevity, 2022 - Wiley Online Library
… We assessed the effect of PGZ on the long-lived glp-1(e2144… function leads to lifespan
extension due to reduced oxygen … The levels of endogenous reactive oxygen species (ROS) …

[HTML][HTML] Sulforaphane promotes C. elegans longevity and healthspan via DAF-16/DAF-2 insulin/IGF-1 signaling

Z Qi, H Ji, M Le, H Li, A Wieland, S Bauer, L Liu… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
… For the evaluation of reactive oxygen species (ROS) levels, 3-day-… Finally, the sulforaphane
treatment of the long-lived … might target the DAF-16/FOXO transcription factor downstream of …

[HTML][HTML] Paeonol promotes longevity and fitness in Caenorhabditis elegans through activating the DAF-16/FOXO and SKN-1/Nrf2 transcription factors

R Li, Q Yi, J Wang, Y Miao, Q Chen, Y Xu… - Biomedicine & …, 2024 - Elsevier
… In addition, paeonol has been demonstrated to decrease intracellular reactive oxygen species
… protective effects under stress may contribute to the longevity extension action of paeonol. …

DAF-16/FoxO in Caenorhabditis elegans and Its Role in Metabolic Remodeling.

A ZečićOrcI, BP Braeckman - Cells (2073-4409), 2020 - search.ebscohost.com
long-lived and supports the idea that daf-2 mutants could potentially rely on the heterochronically
activated dauer survival program for their longevity … levels of reactive oxygen species […

Knockdown of phosphatases of regenerating liver‐1 prolongs the lifespan of Caenorhabditis elegans via activating DAF16/FOXO

Y Yu, J Chen, L An, T Huang, W Wang… - The FASEB …, 2023 - Wiley Online Library
… Yaoru Yu and Jing Chen authors are contributed equally to … and thereby regulates the
lifespan of long- lived animals' cells.… detrimental effects of reactive oxygen species on lifespan: a …

Trigonelline Extends the Lifespan of C. Elegans and Delays the Progression of Age‐Related Diseases by Activating AMPK, DAF‐16, and HSF‐1

WY Zeng, L Tan, C Han, ZY Zheng… - … Cellular Longevity, 2021 - Wiley Online Library
… Trigonelline could not prolong the lifespan of long-lived … The transcription factor DAF-16/FOXO
plays a central role in … damage caused by mitochondrial reactive oxygen species (ROS) …