A review on caspases: key regulators of biological activities and apoptosis
G Sahoo, D Samal, P Khandayataray… - Molecular neurobiology, 2023 - Springer
… elegans and CED-4 protein is the stimulator for CED-3 activation while the CED-9 protein is
… zymogens and contain long pro-domains which allow them to interact with specific signalling …
… zymogens and contain long pro-domains which allow them to interact with specific signalling …
Caspases—at the cutting edge of cell death
HR Stennicke - Programmed Cell Death in Animals and Plants, 2021 - taylorfrancis.com
… shows numerous features that bear more resemblance to the serine proteases than to other
… (1997) Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. …
… (1997) Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. …
The intricate biophysical puzzle of caspase-1 activation
NJ Makoni, MR Nichols - Archives of biochemistry and biophysics, 2021 - Elsevier
… 11 are activated by the non-canonical inflammasome pathway … idea that a protease with a
particular substrate specificity was … IDL, while activation of other caspases involves removal of …
particular substrate specificity was … IDL, while activation of other caspases involves removal of …
Characterization of Caspase 1 Substrate Specificity Utilizing Luminescent Reporter Constructs
N Rohlfes - 2020 - search.proquest.com
… biosensor measuring protease activation has been used … is also non-canonical inflammasomes
that can be activated … the cleavage of the pro-caspase 7 protein by active caspase 1…
that can be activated … the cleavage of the pro-caspase 7 protein by active caspase 1…
[HTML][HTML] The role of caspase family in acute brain injury: the potential therapeutic targets in the future
… -8 activates the apoptotic pathway by cleaving pro-caspase-3 and pro-caspase-7 [21]. …
Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor, which has been tested in the …
Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor, which has been tested in the …
[PDF][PDF] Cathepsin G inhibition by Serpinb1 and Serpinb6 prevents programmed necrosis in neutrophils and monocytes and reduces GSDMD-driven inflammation
… Serpinb6a inhibit the granule serine protease cathepsin G to … PR3 can directly activate
apoptotic pro-caspase-7 and pro-… cells through blockade of cell-specific, CatG-dependent RCD. …
apoptotic pro-caspase-7 and pro-… cells through blockade of cell-specific, CatG-dependent RCD. …
[HTML][HTML] Application of regulatory cell death in cancer: based on targeted therapy and immunotherapy
X Qi, Q Li, X Che, Q Wang, G Wu - Frontiers in immunology, 2022 - frontiersin.org
… the cysteinyl aspartate specific proteinase (caspase) … and non-canonical inflammasome
pathways are the activation of … the activation of pro-caspase-3 and pro-caspase-7 forming …
pathways are the activation of … the activation of pro-caspase-3 and pro-caspase-7 forming …
Programmed cell death in animals and plants
J Bryant, J Garland, SG Hughes - 2021 - books.google.com
… to relate specific apoptotic events or cytokine activation to specific caspases. … features that
bear more resemblance to the serine proteases than to other well described thiol proteases…
bear more resemblance to the serine proteases than to other well described thiol proteases…
Exploring proteomic drug targets, therapeutic strategies and protein-protein interactions in cancer: mechanistic view
… proteomics provides clear evidence about cell type-specific … This activated AKT has a
critical role in role in cell survival … Modifications involve incorporation of non-canonical amino …
critical role in role in cell survival … Modifications involve incorporation of non-canonical amino …
Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner
… a platelet-specific FLNA deficiency … activates the effector caspases, pro-caspase-7 and -3,
to target and destroy cellular proteins [19]. Morphological features of platelet apoptosis include …
to target and destroy cellular proteins [19]. Morphological features of platelet apoptosis include …