… host defense peptide mimetic, brilacidin (BRI) as a synergizer with caspofungin (CAS) against
CAS-sensitive and CAS-resistant isolates of Aspergillus fumigatus, Candida … murine model …

… activity against Aspergillus fumigatus with MIC value of 12.5–50 µg/mL but potent activity
against Candida … ) type and they undergo degranulation in a mouse model of FK, resulting in …

… had reduced candidal burden in the kidneys relative to control mice. In … mimetics have
demonstrated potent activity in pre-clinical laboratory testing and in various animal models of oral …

… I and II in clinical trials for oral candidiasis in HIV patients [18], … in mouse models of sepsis by
immunomodulation of the host … Bio, is a CD28 mimetic that antagonizes CD28 cell signaling […

… some of the antimicrobial peptides with activity against Candida. This could … murine model
of candidiasis and in vitro with a microdilution method, as well as a very low hemolytic activity …

… of MRSA in a neutropenic mouse model. This anti-MRSA activity was attributed to its eight
… showed anti-biofilm activity even at sub-killing concentration against yeast and bacteria (81)…

… mimetics of the peptides, the capacity of HDPs to inhibit viral infections in a number of
ways warrants further examination in these areas in the context of activities against viruses. …

… and has several biological activities related to host defence, including antimicrobial activity.
Its … fumigatus, Cryptococcus neoformans, Candida albicans and Histoplasma capsulatum are …

… activity of an antifungal peptide mimetic … of host defense peptides exhibit potent antifungal
activity, both in vitro and in vivo. Major advantages of these molecules over the parent peptides …

… Kelli Wuerth helped with establishing the mouse model. Dr. Robert EW Hancock supervised
the … Human organoid biofilm model for assessing antibiofilm activity of novel agents. NPJ …