Genomic landscape and clonal evolution of acute myeloid leukemia with t (8; 21): an international study on 331 patients

…, WC Chou, IW Blau, JL Tang, T Zemojtel… - Blood, The Journal …, 2019 - ashpublications.org
… factor acute myeloid leukemia (AML), the most common cytogenetic subtype of AML, is
defined by the presence of t(8;21)(q22;q22) or inv(16)(p13q22)/t(16;16)(p13;q22). AML with t(8;21…

Measurable residual disease monitoring in acute myeloid leukemia with t (8; 21)(q22; q22. 1): results from the AML Study Group

…, VI Gaidzik, N Jahn, T Schroeder… - Blood, The Journal …, 2019 - ashpublications.org
We performed serial measurable residual disease (MRD) monitoring in bone marrow (BM)
and peripheral blood (PB) samples of 155 intensively treated patients with RUNX1-RUNX1T1 …

How I investigate acute myeloid leukemia

D Narayanan, OK Weinberg - International journal of laboratory …, 2020 - Wiley Online Library
… abnormalities are identified—t(8;21)(q22;q22.1), inv(16)(p13.1q22), or … -8 The FC panel
should be comprehensive to distinguish AML, acute lymphoblastic leukemia, and acute leukemia

[HTML][HTML] Core binding factor acute myelogenous leukemia-2021 treatment algorithm

G Borthakur, H Kantarjian - Blood cancer journal, 2021 - nature.com
… Core-binding factor (CBF) acute myeloid leukemia (AML), … the presence of either t(8;21)(q22;q22)
or inv(16)(p13q22)/t(16;16)… both t(8;21) and inv16 AML involve CBF translocations and …

[PDF][PDF] Acute myeloid leukemia: a review

A Pelcovits, R Niroula - Rhode Island medical journal, 2020 - rimed.org
… [t(8;21), inv(16), or t(15;17)].AML is further classified into three prognostic risk groups: favorable,
intermediate, and adverse [Table 1].These are based on both cytogenetics and relatively …

Study of clinical outcome and prognosis in pediatric core binding factor-acute myeloid leukemia

J Wu, AD Lu, LP Zhang, YX Zuo… - Zhonghua xue ye xue za …, 2019 - europepmc.org
… factor-acute myeloid leukemia, CBF-AML)是指一组存在t(8;21)(q22;q22)或inv(16)(p13q22)/t(16…
在儿童AML中,t(8;21)与inv(16)/t(16;16)染色体异常分别占12%,8%,CBF-AML占20%~22%[1].…

Morphological and immunophenotypic clues to the WHO categories of acute myeloid leukaemia

BJ Bain, MC Béné - Acta haematologica, 2019 - karger.com
… Diagnosis and classification of acute myeloid leukaemia (AML) … Most importantly, acute
promyelocytic leukaemia can be … identification of cases associated with t (8; 21), inv (16), t (1; 22), …

Mutated WT1, FLT3-ITD, and NUP98-NSD1 Fusion in Various Combinations Define a Poor Prognostic Group in Pediatric Acute Myeloid Leukemia

N Niktoreh, C Walter, M Zimmermann… - Journal of …, 2019 - Wiley Online Library
translocation of chromosomes 8 and 21 and inversion or translocation of chromosome 16. …
b Other cytogenetic aberrations such as trisomy 8, various chromosomal translocations, and …

[HTML][HTML] CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia

…, GJ Ossenkoppele, S Zweegman, L Smit, T Mutis… - …, 2019 - ncbi.nlm.nih.gov
… tumor burden in acute myeloid leukemia (AML) or T-cell acute lymphoblastic leukemia (T-ALL…
chemotherapy in BALL but not in T-ALL, 8 we also analyzed the expression of CD38 on the …

An update on the molecular pathogenesis and potential therapeutic targeting of AML with t(8;21)(q22;q22.1);RUNX1-RUNX1T1

S Al-Harbi, M Aljurf, M Mohty, F Almohareb… - Blood …, 2020 - ashpublications.org
Acute myeloid leukemia (AML) with t(8;21)(q22;q22.1);RUNX1-RUNX1T1, one of the core-binding
factor leukemias, is one of the most common subtypes of AML with recurrent genetic …