Addition of etoricoxib during concurrent chemo-radiation of cervical cancer patients could result in faster resolution of gross disease: a prospective single-institution …

SS Dhar, UP Shahi, D Kumar, R Mishra… - Indian Journal of …, 2020 - Springer
… -2 inhibitor Etoricoxib during concurrent chemo-radiotherapy schedule of cervical cancer
patients on tumour response and acute toxicities. … Cyclooxygenase-2 inhibitor studies in animal …

[HTML][HTML] COX-2 as a potential biomarker and therapeutic target in melanoma

DV Tudor, I Bâldea, M Lupu, T Kacso… - Cancer biology & …, 2020 - ncbi.nlm.nih.gov
… or radiosensitization. Later we present several studies that focused on evaluating COX-2
inhibitors’ … with rofecoxib, a selective COX-2 inhibitor. Interestingly, after 1 year of treatment with …

COX 2-inhibitors; a thorough and updated survey into combinational therapies in cancers

P Rodrigues, H Bangali, A Hammoud, YF Mustafa… - Medical Oncology, 2024 - Springer
… profile, and production of toxic metabolites from rofecoxib may contribute to its cardiac
toxicity [45]. Research suggests that both NSAIDs and COX-2 inhibitors are associated with an …

Celecoxib in cancer therapy and prevention–review

N Tołoczko-Iwaniuk… - Current Drug …, 2019 - ingentaconnect.com
… One of such potential treatment pathways is cyclooxygenase-2 (COX-2) inhibition, particularly
… The issue of a potential radiosensitizing effect of celecoxib on several types of cancer has …

[PDF][PDF] fhe apoptosis pathway: a drugable target in solid tumors

DJA de Groot - research.rug.nl
… , demonstrating that radiosensitization by celecoxib occurs in … had no effect on the
radiosensitizing effects of celecoxib. Thus, … Inhibition of cyclooxygenase-2 by rofecoxib attenuates …

Gemcitabine, vinorelbine and cyclooxygenase inhibitors in the treatment of glioblastoma. Ultrastructural analyses in C6 glioma in vitro

İ Elmaci, A Bilir, A Ozpinar, MA Altinoz - Tissue and Cell, 2019 - Elsevier
radiosensitizer in high-grade glioma. Some studies showed synergism of anti-inflammatory
cyclooxygenase-inhibitors with microtubule inhibitorsRofecoxib is withdrawn from the market…

12 Drug repurposing of selective COX-2 inhibitors in the pursuit of new therapeutic

N Saha, S Biswas, A Kumar, AK Chakraborti - Drug Repurposing, 2023 - books.google.com
… -2, also known as cyclooxygenase-2 or COX-2, is an enzyme that … The radiosensitizing effect
of celecoxib in the presence of … administration of rofecoxib and creatine inhibited the striatal …

12 Drug repurposing of selective COX-2 inhibitors in the pursuit of new therapeutic avenues

N Saha, S Biswas, A Kumar, AK Chakraborti - Drug Repurposing - degruyter.com
… The radiosensitizing effect of celecoxib in the presence of … administration of rofecoxib and
creatine inhibited the striatal … application of specific cyclooxygenase2 inhibitors. Arthritis …

[PDF][PDF] Efficacy and Safety of Low Dose Celecoxib with Chemoradiation in Locally advanced Head and Neck Squamous Cell Carcinoma

RT Kumar - 2020 - repository-tnmgrmu.ac.in
… In the RTOG 9501 trial, the incidence of acute toxicity of grade 3 or greater was 34 % in the
… The COX - 2 inhibitor rofecoxib ( Vioxx ) was removed from the market in 2004 due to its risk…

[HTML][HTML] Sulfonamides modulating tyrosine kinases-An expedient approach towards novel anticancer agents

R Das, G Tambe, A Shard - Results in Chemistry, 2023 - Elsevier
… In 1990s, sulfonamide cyclooxygenase inhibitors rofecoxibparallel solid-phase synthesis
to develop library of cyclic guanidine-linked sulfonamide derivatives as LMTK3 kinase inhibitors