Research progress on adenosine in central nervous system diseases

YJ Liu, J Chen, X Li, X Zhou, YM Hu… - CNS neuroscience & …, 2019 - Wiley Online Library
Adenosine receptor dysfunction is also involved in the pathology of … , the adenosine receptor
balance theory is important for brain disease treatment. The concentration of adenosine can …

The role of adenosine receptors in the central action of caffeine

JW Daly, D Shi, O Nikodijević… - Caffeine and Behavior …, 2020 - taylorfrancis.com
… -adenosine receptors reduces affinity of dopaminergic agonists for D2-dopamine receptors.…
blockade of tonic adenosine input to both Ax- and A2A-adenosine receptors of the striatum. …

The role of adenosine receptors in mood and anxiety disorders

D van Calker, K Biber, K Domschke… - Journal of …, 2019 - Wiley Online Library
… were later found to encompass two different types of receptors, the … 2B receptors, and an
additional third adenosine receptor subtype (A 3 ) was identified. These four adenosine receptor

Purinergic receptors of the central nervous system: biology, PET ligands, and their applications

H Zarrinmayeh, PR Territo - Molecular Imaging, 2020 - journals.sagepub.com
… mainly effects brain functions through interaction with these 2 receptors, A 1 and A 2A , 64
… of A 2A receptors influences the neuromodulatory effect of adenosine. Adenosine receptors

[HTML][HTML] Targeting adenosine receptors: a potential pharmacological avenue for acute and chronic pain

F Vincenzi, S Pasquini, PA Borea, K Varani - International Journal of …, 2020 - mdpi.com
… identified adenosine receptors (ARs) as potential targets for the management of acute and
chronic pain. Adenosine … on allosteric enhancer activity at the A1 adenosine receptor. J. Med. …

[HTML][HTML] Adenosine and the cardiovascular system: the good and the bad

R Guieu, JC Deharo, B Maille, L Crotti… - Journal of clinical …, 2020 - mdpi.com
… the cardiovascular system. Finally, the effects of adenosine on the cardiovascular system are
… Future research should aim to develop modulating agents of adenosine receptors to slow …

International union of basic and clinical pharmacology. CXII: adenosine receptors: a further update

AP IJzerman, KA Jacobson, CE Müller… - Pharmacological …, 2022 - ASPET
… of adenosine receptors, to examine a multitude of receptor structures and novel ligands,
to gauge new pharmacology, and to evaluate clinical trials with adenosine receptor ligands. …

Therapeutic potential of agonists and antagonists of A1, A2a, A2b and A3 adenosine receptors

S Jamwal, A Mittal, P Kumar… - Current …, 2019 - ingentaconnect.com
… In this review, we have collected and discussed data about the physiological action of
adenosine, adenosine receptors, role of adenosine in pathological conditions, adenosine receptor

Structure and function of adenosine receptor heteromers

R Franco, A Cordomí, C Llinas del Torrent… - Cellular and Molecular …, 2021 - Springer
adenosine in mammals are multiple, and one or more of the four specific adenosine receptors
(… may be ionotropic or metabotropic, four P1 adenosine receptors are all class A members …

[HTML][HTML] Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists

A Martí Navia, D Dal Ben, C Lambertucci, A Spinaci… - Cells, 2020 - mdpi.com
… , in the central nervous system (CNS)… adenosine receptors (ARs) are emerging as an
attractive therapeutic target for modulating brain injury in a variety of animal models of neurological