Adiponectin signalling in bone homeostasis, with age and in disease
Adiponectin is the most abundant circulating adipokine and is primarily involved in glucose
metabolism and insulin resistance. Within the bone, osteoblasts and osteoclasts express the
adiponectin receptors, however, there are conflicting reports on the effects of adiponectin on
bone formation and turnover. Many studies have shown a pro-osteogenic role for
adiponectin in in vivo murine models and in vitro: with increased osteoblast differentiation
and activity, alongside lower levels of osteoclastogenesis. However, human studies often …
metabolism and insulin resistance. Within the bone, osteoblasts and osteoclasts express the
adiponectin receptors, however, there are conflicting reports on the effects of adiponectin on
bone formation and turnover. Many studies have shown a pro-osteogenic role for
adiponectin in in vivo murine models and in vitro: with increased osteoblast differentiation
and activity, alongside lower levels of osteoclastogenesis. However, human studies often …
[PDF][PDF] Adiponectin signalling in bone homeostasis, with age and in
Adiponectin is the most abundant circulating adipokine and is primarily involved in glucose
metabolism and insulin resistance. Within the bone, osteoblasts and osteoclasts express the
adiponectin receptors, however, there are conflicting reports on the effects of adiponectin on
bone formation and turnover. Many studies have shown a pro-osteogenic role for
adiponectin in in vivo murine models and in vitro: with increased osteoblast differentiation
and activity, alongside lower levels of osteoclastogenesis. However, human studies often …
metabolism and insulin resistance. Within the bone, osteoblasts and osteoclasts express the
adiponectin receptors, however, there are conflicting reports on the effects of adiponectin on
bone formation and turnover. Many studies have shown a pro-osteogenic role for
adiponectin in in vivo murine models and in vitro: with increased osteoblast differentiation
and activity, alongside lower levels of osteoclastogenesis. However, human studies often …
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