[HTML][HTML] Body composition in amyotrophic lateral sclerosis subjects and its effect on disease progression and survival

R Tandan, EA Levy, DB Howard, J Hiser… - The American journal of …, 2022 - Elsevier
… Decrease in fat mass (FM) is usually a consequence of catabolism of adipose tissue reserves
for … the utility of computed body composition in predicting disease progression and survival. …

Association Between Fat Depletion and Prognosis of Amyotrophic Lateral Sclerosis: CT‐Based Body Composition Analysis

SJ Choi, SH Yoon, JJ Sung, JH Lee - Annals of Neurology, 2023 - Wiley Online Library
… During disease progression, both skeletal muscles and adipose tissues develop wasting
due to … images of low visceral fat volume (adipopenia) predicting mortality in amyotrophic

Hypermetabolism associated with worse prognosis of amyotrophic lateral sclerosis

J He, J Fu, W Zhao, C Ren, P Liu, L Chen, D Li… - Journal of …, 2022 - Springer
… This finding might attribute hypermetabolism to the quality rather than quantity of muscular
or adipose tissues. One recent study on the biopsies of muscle tissues from patients with ALS …

The hypometabolic state: a good predictor of a better prognosis in amyotrophic lateral sclerosis

M Cattaneo, P Jesus, A Lizio, P Fayemendy… - Journal of Neurology …, 2022 - jnnp.bmj.com
… phase of the disease by reduced adipose tissue accumulation, increased energy expenditure
… . Which equation best predicts energy expenditure in amyotrophic lateral sclerosis? J Am …

Investigation of the prognostic predictive value of serum lipid profiles in amyotrophic lateral sclerosis: roles of sex and hypermetabolism

R Nakamura, M Kurihara, N Ogawa, A Kitamura… - Scientific Reports, 2022 - nature.com
The prognostic predictive value of lipid profiling in amyotrophic lateral sclerosis (ALS) remains
unclear. Here, we aimed to clarify the value of the levels of serum lipids, including high-…

Lower hypothalamic volume with lower body mass index is associated with shorter survival in patients with amyotrophic lateral sclerosis

J Chang, TB Shaw, CJ Holdom… - European Journal of …, 2023 - Wiley Online Library
… (a) Fitted graph for the relationship between BMI and hypothalamic volume and (b) posterior
distributions for the quadratic and linear terms for patients with amyotrophic lateral sclerosis

Body fat percentage and availability of oral food intake: prognostic factors and implications for nutrition in amyotrophic lateral sclerosis

JW Park, M Kim, SH Baek, JH Sung, JG Yu, BJ Kim - Nutrients, 2021 - mdpi.com
fat (ie, adipose tissue). For example, several recent studies in this field have discussed leptin,
a hormone produced by adipocytes, due to its possible neuroprotective role [25,26]. Leptin …

Correlation of weight and body composition with disease progression rate in patients with amyotrophic lateral sclerosis

JY Li, XH Sun, ZY Cai, D Shen, XZ Yang, MS Liu… - Scientific Reports, 2022 - nature.com
… the nutritional status of Chinese patients with amyotrophic lateral sclerosis (ALS), further …
the tendency of visceral adipose tissues depot in ALS patients. Our study found fat in limbs …

Alterations in metabolic biomarkers and their potential role in amyotrophic lateral sclerosis

JY Li, LY Cui, XH Sun, D Shen, XZ Yang… - Annals of Clinical …, 2022 - Wiley Online Library
… Adiponectin and visfatin represent potential biomarkers for prediction of disease … , was
originally known for its secretion from visceral adipose tissue, 59 which was also confirmed in our …

Prognostic prediction by hypermetabolism varies depending on the nutritional status in early amyotrophic lateral sclerosis

R Nakamura, M Kurihara, N Ogawa, A Kitamura… - Scientific reports, 2021 - nature.com
… To examine whether hypermetabolism could predict the prognosis of early amyotrophic
lateral sclerosis (ALS) patients with differing nutritional profiles. This single-center, retrospective …