… It can be expected that structural biology, particularly because of advance in cryo-EM, will
continue to unveil the acting mechanisms of this fascinating family of proteins. …

… of NOD-like receptors (NLRs) has blossomed over the past two decades, with much being
learned about the ligands and conditions that stimulate the NLRs and the outcomes of NLR …

… Recently, a rapid progress in the study of intracellular sensors that exist … biology studies
using X-ray crystallography and cryo-electron microscopy (EM) have made remarkable progress …

… progress has been done in studying the structure of TLRs/NLRs in higher eukaryotes; however,
structural studies on fish innate immune receptors are … Unlike the fundamental progress …

… Finally, we highlight major advances in NLR structural biology, including the structures of …
inform our understanding of NLR-triggered immune signalling and associated host cell death. …

… most well-defined NLR proteins and highlight their association and biological impact on a
… Prostate Higher expression in advanced prostate cancer submitted to androgen deprivation …

… play important roles in distinct biological processes such as the … summarize recent research
advances on NLR signaling and … revealed that NLR signaling was a key biological pathway …

… on NOD-like receptors or NLRs that act in tandem with other transmembrane and intracellular
receptors … In teleosts, whole genome sequencing along with advanced bioinformatics tools …

… -I receptor is associated with pseudogene 5S rRNA-mainly RNA5SP141 transcription products.
The biological … RLRs is ongoing among patients with advanced solid tumors refractory to …

… of these molecules by immune receptors, to the subsequent post-… Recent advances in the
field are discussed, as well as the … and biological assays to investigate these critical receptors …