The negative impact of the environment on methylation/epigenetic marking in gametes and embryos: A plea for action to protect the fertility of future generations

Y Menezo, B Dale, K Elder - Molecular Reproduction and …, 2019 - Wiley Online Library
… is finite and decreases with age. Ejaculated sperm has no … Endocrine disrupting
chemicals can interfere with female … An area of major concern is the potential interaction/synergy …

Reproductive aging: biological pathways and potential interventive strategies

Y Liu, J Gao - Journal of Genetics and Genomics, 2023 - Elsevier
… These factors can impair gamete quality and quantity through … and thus potentially affect
embryo developmental capacity … have been tested to intervene in reproductive aging, mainly by …

[HTML][HTML] Gamete quality in a multistressor environment

A Gallo, R Boni, E Tosti - Environment international, 2020 - Elsevier
possible sources of environmental stress that impair gamete … and interfere with physiological
processes to exert toxic effects on … has been tested on gametes and embryos of the common …

Ovarian aging: mechanisms and intervention strategies

Z Zhu, W Xu, L Liu - Medical Review, 2023 - degruyter.com
… , where genetic as well as environmental factors influence its … development and reserve during
fetal development and in … an alternative source of gametes for reproduction and rebuilding …

How the environment affects early embryonic development

MA Sirard - Reproduction, Fertility and Development, 2021 - CSIRO Publishing
… changes that influence the phenotype of gametes, embryos, … so we could focus on the ones
directly affected by the age of … a therapeutic intervention that may be applied to early embryos

Maternal age affects oocyte developmental potential at both ends of the age spectrum

RL Krisher - Reproduction, Fertility and Development, 2019 - CSIRO Publishing
… It is unclear if or how this changing endocrine environment affects oocytes in the remaining
follicles. What is clear across species, from nematodes (Andux and Ellis 2008) to humans (…

Effect of advanced parental age on pregnancy outcome and offspring health

C Zhang, L Yan, J Qiao - Journal of assisted reproduction and genetics, 2022 - Springer
affect the maturation of gametes and the development of embryos, and therefore the effects
of aging … be affected by environmental alterations and reduced in number. Second, advanced …

Impact of gamete health on fertilization and embryo development: An overview

JB Chorya, TV Sutaria, RK Chaudhari… - Asian Pacific Journal …, 2022 - journals.lww.com
… by various factors like genetics, age, heat stress, in vitro … The abnormal head morphology
could interfere with motility … activity, chromatin integrity, and reproductive potential[ 33 34 35 ]. …

Male age interferes with embryo growth in IVF treatment

J Van Opstal, S Fieuws, C Spiessens… - Human …, 2021 - academic.oup.com
… Female age is well known to interfere with reproductive … thawed sperm samples, no donor
gametes, no vasectomy and no … -related environmental influences during in-utero development …

Epigenetic aging of mammalian gametes

M Klutstein, N Gonen - Molecular Reproduction and …, 2023 - Wiley Online Library
… in the cellular and external environment. Similar to genetic … prospective donor is over 34
years of age, the age of the … Male age negatively impacts embryo development and reproductive …