… and compare the bronchial bacterial load related to cell … in bronchial biopsies of stable COPD
patients with rapid vs slow vs no … We defined rapid decline as rate of FEV1 decline >70 ml/…

… cohort follow-up, and we did not quantify bacterial load but used instead a cut-off point of …
Airway bacterial load and FEV 1 decline in patients with chronic obstructive pulmonary disease…

… Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease (…
UK centers, that baseline airway dysbiosis in COPD patients, characterized by the enrichment …

… A pathogenic role of bacterial load leading to bronchial … to decline in absolute numbers in
AATD-AT patients compared … a reduction in neutrophil accumulation in the lower airways and …

… bacterial richness and diversity in stool samples changed significantly when the FEV 1 declined
more than 40 ml/year (decline … control (Bacteroidetes) and decline (Firmicutes) groups. …

… of bacteria and the microbiota composition in COPD airways … the airways’ bacterial load and
the bronchial inflammation has … in COPD patients’ airways further contributes to reduction of …

… Data on bacterial load in positive cultures were sparingly … FEV1 data were reported across
most studies as mean FEV1 (… in airways disease, such as aspergillus, are not bacteria and …

… volume in 1 s (FEV1) only. This … of airway bacteria occurring during acute exacerbations
of COPD [10,11,12]. An increased bacterial load has been associated with a decline in lung …

… concentration in the bronchial tree, decreasing the bacterial load in the airways and favoring
… Mean FEV1(%) = 43% Reduction in total numbers of sputum cells and neutrophil elastase. …

… decrease the oral bacterial burden compared to samples obtained after an overnight fast. …
Despite analyzing FEV1pp as a continuous variable, inclusion of this subject with a FEV1/FVC …