[HTML][HTML] … derived from human bone marrow mesenchymal stem cells stimulated by deferoxamine accelerate cutaneous wound healing by promoting angiogenesis

J Ding, X Wang, B Chen, J Zhang… - BioMed research …, 2019 - ncbi.nlm.nih.gov
… determination of blood vessel density in the wound sites on … implicated for miR-126 in
development of vascular tissues [26]. … PI3K/AKT pathway and enhance skin wound recovery in the …

Extracellular vesicles from adipose-derived stem cells promote diabetic wound healing via the PI3K-AKT-mTOR-HIF-1α signaling pathway

W Liu, Y Yuan, D Liu - Tissue Engineering and Regenerative Medicine, 2021 - Springer
… the dysfunctions of vascular endothelial cells … essential for wound healing [25, 26]. In this
study, hADSC-EVs could serve as an agonist of HIF-1α for angiogenesis and wound healing. …

A multifunctional role of leucine-rich α-2-glycoprotein 1 in cutaneous wound healing under normal and diabetic conditions

C Liu, MHY Teo, SLT Pek, X Wu, ML Leong, HM Tay… - Diabetes, 2020 - Am Diabetes Assoc
… NETosis in an Akt-dependent manner through TGFβ type I … role in dermal angiogenesis
during wound healing, day 7 wound … observed reduced blood vessel density in the wound bed of …

Ezrin regulates synovial angiogenesis in rheumatoid arthritis through YAP and Akt signalling

Q Chen, K Fan, X Chen, X Xie, L Huang… - Journal of Cellular …, 2021 - Wiley Online Library
… an important role in vascular endothelial cell migration and tube formation through regulation
… cell proliferation and angiogenesis as well as induce vascular development. After entering …

[HTML][HTML] Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis

H Nosrati, R Aramideh Khouy, A Nosrati… - Journal of …, 2021 - Springer
… of vessels, causes vascular maturation, and keeps integrity … by activation of Akt and protein
kinase B through the P13K … membrane for vascular regeneration in wound healing [106]. …

[HTML][HTML] Pathological angiogenesis: mechanisms and therapeutic strategies

AC Dudley, AW Griffioen - Angiogenesis, 2023 - Springer
… Here, we provide an overview of recent insights into blood vessel development and … occurs
through PECAM-1-mediated activation of NF-kB and Akt, is an important regulator of vascular

Platelet‐derived growth factor‐AA is a substantial factor in the ability of adipose‐derived stem cells and endothelial progenitor cells to enhance wound healing

LW Wu, WL Chen, SM Huang, JYH Chan - The FASEB Journal, 2019 - Wiley Online Library
… to improve wound healing through the PI3K/Akt/eNOS … enhancing wound healing, possibly
by its effects on angiogenesis. It … play important roles in affecting tumor growth, blood vessel

Bone marrow-derived mesenchymal stem cells combined with simvastatin accelerates burn wound healing by activation of the Akt/mTOR pathway

P Ramhormozi, J Mohajer Ansari… - Journal of Burn Care …, 2020 - academic.oup.com
… Burn wound healing is one of the most important problems in … is expressed early in blood
vessel development and plays a … not only promoted angiogenesis but also activated Akt/mTOR …

Therapeutic strategies for enhancing angiogenesis in wound healing

AP Veith, K Henderson, A Spencer, AD Sligar… - Advanced drug delivery …, 2019 - Elsevier
… -healing wounds in diabetes and peripheral vascular disease … Macrophages are essential
to the coordinate the angiogenic … to angiogenic growth factors during the development of …

[PDF][PDF] Langerhans cells are essential components of the angiogenic niche during murine skin repair

R Wasko, K Bridges, R Pannone, I Sidhu, Y Xing… - Developmental cell, 2022 - cell.com
… blood vessels from existing vasculature, is an essential feature of tissue development and
… whether LCs function in skin wound repair, and specifically in angiogenesis. Consistent with …