Ca2+ homeostasis dysregulation in Alzheimer's disease: a focus on plasma membrane and cell organelles
X Wang, W Zheng - The FASEB Journal, 2019 - Wiley Online Library
… However, the cleavage of STIM2, the major isoform in hippocampus, was not examined in
… of MAM and its alteration in AD pathogenesis. Bridged by glucose-regulated protein 75, the …
… of MAM and its alteration in AD pathogenesis. Bridged by glucose-regulated protein 75, the …
The role of DISC1 in the organization of the T-cell immunological synapse
NA Maskalenko - 2019 - repositories.lib.utexas.edu
… and is needed for abundant actin filaments at the IS..75 … the insertion of the NsiI restriction
site (a modified vector we … in the DISC1 KD, which made us question whether DISC1 was …
site (a modified vector we … in the DISC1 KD, which made us question whether DISC1 was …
Nanoscale surveillance of the brain by microglia via cAMP-regulated filopodia
LP Bernier, CJ Bohlen, EM York, HB Choi, A Kamyabi… - Cell reports, 2019 - cell.com
… by increased cAMP and that disrupting cAMP compartmentalization alters and increases
the surface distribution of filopodia. Our work, therefore, describes intracellular cAMP signaling …
the surface distribution of filopodia. Our work, therefore, describes intracellular cAMP signaling …
[HTML][HTML] Opposite regulation of glycogen metabolism by cAMP produced in the cytosol and at the plasma membrane
PFV Bizerra, EH Gilglioni, HL Li, S Go… - … et Biophysica Acta (BBA …, 2024 - Elsevier
… The cAMP standards for the competitive ELISA were prepared in a modified assay diluent
(… Immunoblotting showed that HepG2 cells expressed a 75 kD sAC isoform, which was …
(… Immunoblotting showed that HepG2 cells expressed a 75 kD sAC isoform, which was …
Spatial organization of palmitoyl acyl transferases governs substrate localization and function
JM Philippe, PM Jenkins - Molecular membrane biology, 2019 - Taylor & Francis
… of specific proteins along intercalated discs and T-tubules to … context, or PAT subcellular
localization, governs substrate … -associated substrates and pathways are altered as a result of …
localization, governs substrate … -associated substrates and pathways are altered as a result of …
Roles of Phosphorylation of N-Methyl-d-Aspartate Receptor in Chronic Pain
L Pan, T Li, R Wang, W Deng, H Pu, M Deng - Cellular and Molecular …, 2023 - Springer
… and differentially affect the subcellular distribution of GluN1. … density—95, disks—large,
and zonula occludens—1)-binding … Then, the phosphorylated CREB combines with the cAMP …
and zonula occludens—1)-binding … Then, the phosphorylated CREB combines with the cAMP …
GPCRs in intracellular compartments: New targets for drug discovery
I Fasciani, M Carli, F Petragnano, F Colaianni, G Aloisi… - Biomolecules, 2022 - mdpi.com
… for the calcium sensing receptor [75], the secretin receptor [76]… signaling in real time without
altering the cell homeostasis. … [26] examined the subcellular distribution of the activated β2 …
altering the cell homeostasis. … [26] examined the subcellular distribution of the activated β2 …
SIRT1 activation and its effect on intercalated disc proteins as a way to reduce doxorubicin cardiotoxicity
E Podyacheva, Y Toropova - Frontiers in Pharmacology, 2022 - frontiersin.org
… To date, four isoforms of desmoglein (Dsg 1–4) and three isoforms of desmocollin (Dsc 1–3) …
These mice showed altered ID structures with increased expression of α-, β-catenin, …
These mice showed altered ID structures with increased expression of α-, β-catenin, …
cAMP-dependent synaptic plasticity at the hippocampal mossy fiber terminal
M Shahoha, R Cohen, Y Ben-Simon… - Frontiers in Synaptic …, 2022 - frontiersin.org
… and syn2 genes, encoding the main isoforms expressed in CNS neurons, did not alter
cAMP-dependent LTP or FSK-induced potentiation (Figure 3B and Table 1; Spillane et al., 1995). …
cAMP-dependent LTP or FSK-induced potentiation (Figure 3B and Table 1; Spillane et al., 1995). …
Elucidating the Role of Endocytosis in cAMP-dependent Transcription
GE Peng - 2019 - search.proquest.com
… of the cAMP signaling cascade using primarily spinning disk … I additionally generated
modified constructs complementary … a second isoform of the catalytic subunit of cAMP-dependent …
modified constructs complementary … a second isoform of the catalytic subunit of cAMP-dependent …