… which regulates the surface expression of CD4 on … TCRζ, have been associated with T cell
activation upon TCR stimulation. Similar to HERV-E clone 4-1, also HRES-1/Rab4 expression …

… /or miRs expressed in rAAV may be an excellent alternative to … patients, but almost always
ultimately result in acquired resistance. rAAV’s ability to provide long-term genetic expression …

… additionally armored with genes that enable, for example, the expression of cytokines. …
alternative splicing occurred with rare frequency. Therefore, acquired mutations and alternative …

… of recurrent chronic myeloid leukemia 26 in patients after allogeneic … (EBV)-associated
posttransplant lymphoproliferative disease … The alternatives to viral gene transfer technologies are …

… alternative exon splicing or point mutations, which, although well described in B-ALL,
have not been reported to alter the expression … Although the factors associated with CD19-negative …

… Finally, alternative approaches are suggested to circumvent these problems. … of anergy,
84 as well as downregulation of the TCRζ chain, which impairs the cytotoxic effector function of …

… leukemia (ALL) and for the treatment of patients experiencing minimal residual disease (MRD)
[30]. Its efficiency in the treatment of acute myeloid leukemia (… CARs with alternative co-…

… Genetic abnormalities that trigger the aberrant expression of LMO2 and other members of
… DNA and regulates gene expression. Importantly, we identified many genes of transcription …

… inhibition of target gene to achieve functional outcomes that could be potentially applied as
an alternative therapeutic approach … and acute myeloid leukemias) for therapeutic purposes. …

… Preclinical studies have shown that many alternative immune CAR cells with a high … I trials
in patients with relapsed or resistant acute myeloid leukemia. Additional expression of a CAR …