… study was to conduct a systematic review in order to describe the regulatory mechanisms of
alternative splicing, … Finally, recent advances in therapeutics targeting splicing catalysis and …

… Alternative splicing might be associated with susceptibility to cancers, cardiovascular diseases…
the analysis of directly spliced isoform structures as well as the discovery of thousands of …

… During the first decades after the discovery of alternative splicing, many specific alternative
… in this Review. Following an overview of the basic mechanisms of alternative splicing, we …

… diseases, and … splicing events and how this leads to disease is vital for designing effective
therapeutic strategies. In this review, we focus on advances in therapies targeting splicing, and …

… by alternative splicing mechanisms. This review focuses on the alternative spliced isoforms
of … yield some exciting findings and possible options for splicing-targeted angiogenic therapy. …

… disease that involves malignant transformation. In this review, we consider alternative splicing
events in … cells, and discuss current therapies to treat cancer-related to alternative splicing. …

… of the spliceosome), and the high degree of alternative splicing seen in tetralogy of Fallot
samples (… in modulating CVD phenotypes, we highlight some recent developments in this area. …

… The complexity of splicing regulation allows for multiple therapeutic approaches to correct
disease-associated mis-splicing events. In this review, we first highlight recent findings from …

… -related diseases including cardiovascular disease, … review, we summarize key findings
and provide our insights on the role of RNA splicing in aging and longevity with a focus on recent …

… complex known as the spliceosome mediates canonical splicing. Due to alternative splicing,
a … This finding is supported by a more recent study where patients with low blood MICRA …