[HTML][HTML] Biomarkers and phenotypic expression in Alzheimer's disease: exploring the contribution of frailty in the Alzheimer's Disease Neuroimaging Initiative

…, G Bruno, Alzheimer's Disease Neuroimaging Initiative - Geroscience, 2021 - Springer
… that frailty, quantified as FI, can influence the neuropathological and biological changes
occurring with brain aging and neurodegeneration and the relationship with their phenotypic

[HTML][HTML] X chromosome-wide association study of quantitative biomarkers from the Alzheimer's Disease Neuroimaging Initiative study

…, Alzheimer's Disease Neuroimaging Initiative - Frontiers in Aging …, 2023 - frontiersin.org
… with the quantitative biomarkers of the AD. Follow-up study in molecular genetics is needed
to … test statistic to detect the SNP effect on the phenotypic means (respectively denoted by T …

[HTML][HTML] Genome-wide association study of quantitative biomarkers identifies a novel locus for Alzheimer's disease at 12p12. 1

…, Alzheimer's Disease Neuroimaging Initiative ehdrake … - BMC genomics, 2022 - Springer
Genetic study of quantitative biomarkers in Alzheimer’s Disease (AD) is a promising method
to identify novel genetic … In particular, the genetic effect of this SNP on the AD phenotype is …

Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease

…, Alzheimer's Disease Neuroimaging … - Alzheimer's & …, 2022 - Wiley Online Library
… AD risk has been implicated by genetics, fluid biomarker, and other approaches using …
disease progression score was used as a quantitative phenotype in a genome-wide association

[HTML][HTML] … of Alzheimer's disease brain imaging biomarkers and neuropsychological phenotypes in the European medical information framework for Alzheimer's disease …

J Homann, T Osburg, O Ohlei, V Dobricic… - Frontiers in aging …, 2022 - frontiersin.org
… An overview of the quantitative phenotypes investigated in … related to neurocognitive function
and structural brain imaging. … the genetic forces underlying AD and related phenotypes. …

Longitudinal neuroimaging biomarkers differ across Alzheimer's disease phenotypes

I Sintini, J Graff-Radford, ML Senjem, CG Schwarz… - Brain, 2020 - academic.oup.com
… MoCA scores, as a quantitative measure of disease severity. … atrophy patterns in Alzheimer's
disease phenotypes. SPM … log Jacobians) for typical Alzheimer's disease (AD), PCA and …

Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non‐demented individuals

L Lorenzini, LE Collij, N Tesi… - Alzheimer's & …, 2024 - Wiley Online Library
… alterations in quantitative MRI-derived phenotypes, independently … and quantified global and
pathway-GRSs from genetic data in a … from the Alzheimer’s disease neuroimaging initiative. …

[HTML][HTML] A review of brain imaging biomarker genomics in Alzheimer's disease: implementation and perspectives

L Li, X Yu, C Sheng, X Jiang, Q Zhang, Y Han… - Translational …, 2022 - Springer
… multimodal imaging phenotypes with genetic data in a … important roles in quantitative
assessment of biomarkers and … from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) …

Strategies for multivariate analyses of imaging genetics study in Alzheimer's disease

J Sheng, L Wang, H Cheng, Q Zhang, R Zhou… - Neuroscience Letters, 2021 - Elsevier
… the Alzheimer’s Disease Neuroimaging Initiative (ADNI) genetic associations with quantitative
disease … novel targets for future pharmaceutical therapy and biomarker development. …

Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative

…, Alzheimer's Disease Neuroimaging Initiative - Alzheimer's & …, 2019 - Elsevier
… (ADNI) is to validate biomarkers for Alzheimer's disease (AD) … -wide association study (GWAS)
era, new genetic strategies … ADNI multimodal quantitative phenotypes have enabled a …