Transcriptomics of the Rooibos (Aspalathus linearis) Species Complex

EA Stander, W Williams, Y Mgwatyu, P Heusden… - BioTech, 2020 - mdpi.com
… and orientin (the two oxidation products of aspalathin), luteolin, … Wild rooibos plants were
shown to have distinct chemical … wild rooibos plants were found not to produce aspalathin at all. …

Comprehensive in vitro antidiabetic screening of Aspalathus linearis using a target-directed screening platform and cellomics

NA Pringle, M van de Venter, TC Koekemoer - Food & Function, 2021 - pubs.rsc.org
… An aspalathin-enriched green rooibos extract and a fermented extract of A. … survival in
INS-1 β-cells under conditions of severe oxidative stress. In addition, both green and fermented …

[HTML][HTML] Aspalathin alleviates skeletal muscle insulin resistance and mitochondrial dysfunction

SE Mazibuko-Mbeje, SXH Mthembu… - Physiological …, 2022 - ncbi.nlm.nih.gov
… of bioactive compounds found in rooibos (Aspalathus linearis) in … explored the ameliorative
effects of aspalathin, the major … at the therapeutic effects of aspalathin against oxidative stress-…

[PDF][PDF] Effects of aspalathin on insulin resistance and mitochondrial dysfunction in cultured skeletal muscle cells-1 potential implications for type 2 diabetes mellitus …

SE Mazibuko-Mbeje, SX Mthembu, CJ Muller… - Physiological …, 2022 - biomed.cas.cz
… bioactive compounds found in rooibos 65 (Aspalathus linearis) in … explored the ameliorative
effects of aspalathin, the major … therapeutic effects of aspalathin against 364 oxidative stress-…

Evaluating the neuroprotective effects of fermented rooibos herbal tea in Wistar rats exposed to bisphenol-a during gestation and lactation

BK Gamoudi - 2019 - etd.uwc.ac.za
… protective effects of fermented rooibos (Aspalathus linearis) … of its polyphenolic compounds,
especially aspalathin. The anti… of rooibos herbal tea through the amelioration of the effects of …

Aspalathin, a Primary Rooibos Flavonoid, Alleviates Mast Cell-Mediated Allergic Inflammation by the Inhibition of FcεRI Signaling Pathway

Y Kim, S Lee, M Jin, YA Choi, JK Choi, TK Kwon… - Inflammation, 2024 - Springer
… In this study, we demonstrated the effect of ASP, a major rooibos flavonoid, on mast cell-mediated
allergic inflammation. It was confirmed that ASP not only alleviated mast cell-mediated …

Rooibos Aspalathus linearis – can it reduce the incidence and severity of acute mountain sickness? A case study of Aconcagua (6962 m) climbing expedition …

SEH Davies, JL Marnewick, S West - African Journal for Physical …, 2019 - journals.co.za
… Given that physical exercise could exacerbate the effects of oxidative stress at high altitude
as … as an effective and safe supplement for the amelioration of AMS for persons ascending to …

Rooibos tea—in the cross fire of ROS, mitochondrial dysfunction and loss of proteostasis—positioned for healthy aging

C Smit, S De Wet, T Barron, B Loos - Biogerontology, 2023 - Springer
Aspalathus linearis, also commonly known as rooibos, is an … Indeed, model systems of
severe oxidative stress present … , aspalathin derived from rooibos has shown to target stress and …

Aspalathin ameliorates doxorubicin-induced oxidative stress in H9c2 cardiomyoblasts

SC Shabalala, PV Dludla, CJF Muller, X Nxele… - Toxicology in Vitro, 2019 - Elsevier
Aspalathin (ASP) is a C-dihydrochalcone abundantly found in Aspalathus linearis. While we
… -induced apoptosis through the amelioration of oxidative stress in H9c2 cardiomyoblasts. …

The synergistic and neuroprotective effects of alcohol–antioxidant treatment on blood–brain barrier endothelial cells

D Fisher, KA Thomas… - Alcoholism: Clinical and …, 2020 - Wiley Online Library
… ) in the fermented Aspalathus linearis (Rooibos; Rf) tincture … ability of the potent Aspalathin
linearis tincture (Rf), in … AOs, would result in the amelioration of the negative effects of alcohol. …